The Hierarchical Catalog of Orthologs
OrthoDB presents a catalog of orthologous protein-coding genes across 52 vertebrates, 45 arthropods, 142 fungi, 13 basal metazoans, and 1115 bacteria. Orthology refers to the last common ancestor of the species under consideration, and thus OrthoDB explicitly delineates orthologs at each radiation along the species phylogeny. The database of orthologs presents available protein descriptors, together with Gene Ontology and InterPro attributes, which serve to provide general descriptive annotations of the orthologous groups, and facilitate comprehensive orthology database querying.
Now published in NAR.
Please note, due to a technical glitch with the initial OrthoDB6 release we have had to reload the orthologous group data and reassign identifiers. The new datasets are available from the downloads page and we apologise for any inconvenience caused.
Search OrthoDB: "Cytochrome P450" protease | peptidase kinase -serine FBgn0036816 IPR017981 GO:0006950
For detailed instructions on OrthoDB search functions, data sources, and further information, please see Help. Email support[at]orthodb.org for further help.
OrthoDB5 2011: 48 vertebrates, 33 arthropods, 73 fungi, and 12 basal metazoans
OrthoDB4 2010: 44 vertebrates, 25 arthropods, 46 fungi, and 5 basal metazoans
OrthoDB3 2009: 40 vertebrates, 23 arthropods, and 32 fungi
OrthoDB2 2008: 15 vertebrates, 20 arthropods, and 23 fungi
Waterhouse RM, Zdobnov EM, Tegenfeldt F, Li J, Kriventseva EV.
OrthoDB: a hierarchical catalog of animal, fungal and bacterial orthologs.
NAR, Nov 2012, PMID:23180791
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BUSCO Benchmarking sets of Universal Single-Copy Orthologs.
Downloads Protein sequences and orthologous group annotations for major clades.
Species List View all species in the current OrthoDB release.
Citation List View articles that cite OrthoDB.
Browse mapped orthologs from:
Pelodiscus sinensis the Chinese softshell turtle.
Xiphophorus maculatus the southern platyfish.
Mustela putorius the domesticated ferret.
This work by E Zdobnov lab is licensed under a Creative Commons Attribution 3.0 Unported License.