top500_daphnia_iprs

Top 500 InterPro hits

statistically significant differences in comparison to Tribolium are marked in bold (p-value of chi-square test < 0.01 without correction for multiple tests).
Daphnia pulex
(14090 genes with domains)
Apis mellifera
(8077 genes with domains)
Tribolium castaneum
(10451 genes with domains)
FamilyGO terms
794 (1)487 (1)706 (1)IPR007087: Zinc finger, C2H2-typeMolecular Function: nucleic acid binding (GO:0003676), Cellular Component: intracellular (GO:0005622), Molecular Function: zinc ion binding (GO:0008270)
712 (2)397 (2)504 (2)IPR000694: Proline-rich region
314 (3)98 (10)140 (10)IPR002110: Ankyrin
292 (4)35 (38)113 (13)IPR000618: Insect cuticle proteinMolecular Function: structural constituent of cuticle (GO:0042302)
256 (5)176 (4)179 (7)IPR001680: WD-40 repeat
236 (6)162 (5)192 (6)IPR003593: AAA+ ATPase, coreMolecular Function: nucleotide binding (GO:0000166), Molecular Function: nucleoside-triphosphatase activity (GO:0017111)
219 (7)73 (17)77 (21)IPR000210: BTBMolecular Function: protein binding (GO:0005515)
206 (8)198 (3)302 (3)IPR001611: Leucine-rich repeatMolecular Function: protein binding (GO:0005515)
194 (9)124 (7)149 (9)IPR007110: Immunoglobulin-like
178 (10)100 (9)153 (8)IPR002988: G-related albumin-binding GA protein
172 (11)68 (20)92 (16)IPR000276: Rhodopsin-like GPCR superfamilyMolecular Function: rhodopsin-like receptor activity (GO:0001584), Biological Process: G-protein coupled receptor protein signaling pathway (GO:0007186), Cellular Component: integral to membrane (GO:0016021)
130 (12)1 (1343) ()IPR001073: Complement C1q protein
124 (13)76 (16)81 (19)IPR001650: Helicase, C-terminalMolecular Function: nucleic acid binding (GO:0003676), Molecular Function: helicase activity (GO:0004386), Molecular Function: ATP binding (GO:0005524)
123 (14)110 (8)193 (5)IPR007114: Major facilitator superfamilyMolecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: integral to membrane (GO:0016021)
117 (15)20 (86)30 (74)IPR000859: CUB
106 (16)86 (12)94 (15)IPR006210: EGF
105 (17)21 (85)19 (134)IPR007125: Histone coreMolecular Function: DNA binding (GO:0003677)
103 (18)10 (223)74 (24)IPR005135: Endonuclease/exonuclease/phosphatase
100 (19)14 (148)11 (254)IPR008160: Collagen triple helix repeatCellular Component: cytoplasm (GO:0005737), Biological Process: phosphate transport (GO:0006817)
96 (20)57 (26)59 (32)IPR000357: HEAT
91 (21)43 (32)56 (35)IPR002557: Chitin binding Peritrophin-ACellular Component: extracellular region (GO:0005576), Biological Process: chitin metabolic process (GO:0006030), Molecular Function: chitin binding (GO:0008061)
90 (22)4 (538)5 (508)IPR001503: Glycosyl transferase, family 10Biological Process: protein amino acid glycosylation (GO:0006486), Molecular Function: fucosyltransferase activity (GO:0008417), Cellular Component: membrane (GO:0016020)
90 (23)79 (14)95 (14)IPR002048: Calcium-binding EF-handMolecular Function: calcium ion binding (GO:0005509)
85 (24)78 (15)86 (18)IPR001849: Pleckstrin-like
83 (25)73 (18)76 (22)IPR013684: Miro-likeMolecular Function: GTP binding (GO:0005525), Cellular Component: intracellular (GO:0005622), Biological Process: small GTPase mediated signal transduction (GO:0007264)
82 (26)43 (33)58 (33)IPR013229: PEGA
80 (27)93 (11)126 (12)IPR001781: LIM, zinc-bindingMolecular Function: zinc ion binding (GO:0008270)
77 (28)81 (13)92 (17)IPR013026: Tetratricopeptide region
76 (29)68 (21)75 (23)IPR001478: PDZ/DHR/GLGFMolecular Function: protein binding (GO:0005515)
72 (30)56 (27)71 (26)IPR003961: Fibronectin, type III
71 (31)33 (41)39 (51)IPR000387: Tyrosine specific protein phosphatase and dual specificity protein phosphataseBiological Process: dephosphorylation (GO:0016311), Molecular Function: phosphoric monoester hydrolase activity (GO:0016791)
68 (32)45 (30)80 (20)IPR002198: Short-chain dehydrogenase/reductase SDRBiological Process: metabolic process (GO:0008152), Molecular Function: oxidoreductase activity (GO:0016491)
65 (33)51 (28)137 (11)IPR001128: Cytochrome P450Molecular Function: monooxygenase activity (GO:0004497), Molecular Function: iron ion binding (GO:0005506), Biological Process: electron transport (GO:0006118), Molecular Function: heme binding (GO:0020037)
65 (34)69 (19)72 (25)IPR001452: Src homology-3
65 (35)28 (53)35 (59)IPR001810: Cyclin-like F-box
65 (36)37 (36)53 (38)IPR002172: Low density lipoprotein-receptor, class A
61 (37)4 (535)3 (768)IPR001404: Heat shock protein Hsp90Biological Process: protein folding (GO:0006457), Molecular Function: unfolded protein binding (GO:0051082)
60 (38)60 (24)57 (34)IPR001092: Basic helix-loop-helix dimerisation region bHLHCellular Component: nucleus (GO:0005634), Molecular Function: transcription regulator activity (GO:0030528), Biological Process: regulation of transcription (GO:0045449)
60 (39)44 (31)40 (50)IPR011016: RINGv
59 (40)62 (23)66 (28)IPR001440: Tetratricopeptide TPR_1
59 (41)11 (192)10 (272)IPR006553: Leucine-rich repeat, cysteine-containing subtype
58 (42)51 (29)49 (40)IPR002017: Spectrin repeat
53 (43)6 (358)28 (81)IPR000668: Peptidase C1A, papain C-terminalBiological Process: proteolysis (GO:0006508), Molecular Function: cysteine-type peptidase activity (GO:0008234)
53 (44)20 (88)25 (97)IPR001320: Ionotropic glutamate receptorMolecular Function: ionotropic glutamate receptor activity (GO:0004970), Molecular Function: glutamate-gated ion channel activity (GO:0005234), Cellular Component: membrane (GO:0016020)
52 (45)30 (44)36 (57)IPR003595: Protein tyrosine phosphatase, catalytic regionMolecular Function: protein tyrosine phosphatase activity (GO:0004725)
52 (46)58 (25)63 (29)IPR013105: Tetratricopeptide TPR_2
51 (47)64 (22)60 (31)IPR011511: Variant SH3
50 (48)41 (34)55 (36)IPR005821: Ion transportMolecular Function: ion channel activity (GO:0005216), Biological Process: ion transport (GO:0006811), Cellular Component: membrane (GO:0016020)
49 (49)11 (187)18 (137)IPR001304: C-type lectinMolecular Function: sugar binding (GO:0005529)
49 (50)21 (80)17 (151)IPR002893: Zinc finger, MYND-typeMolecular Function: zinc ion binding (GO:0008270)
49 (51)21 (83)22 (113)IPR004087: KHMolecular Function: nucleic acid binding (GO:0003676)
48 (52)19 (97)33 (67)IPR000873: AMP-dependent synthetase and ligaseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolic process (GO:0008152)
48 (53)13 (158)14 (195)IPR003347: Transcription factor jumonji/aspartyl beta-hydroxylase
47 (54)6 (378)10 (269)IPR002659: Glycosyl transferase, family 31Biological Process: protein amino acid glycosylation (GO:0006486), Molecular Function: galactosyltransferase activity (GO:0008378), Cellular Component: membrane (GO:0016020)
46 (55)26 (59)32 (71)IPR001752: Kinesin, motor regionMolecular Function: microtubule motor activity (GO:0003777), Molecular Function: ATP binding (GO:0005524), Cellular Component: microtubule associated complex (GO:0005875), Biological Process: microtubule-based movement (GO:0007018)
45 (56)19 (95)33 (66)IPR000073: Alpha/beta hydrolase fold-1
45 (57)22 (74)51 (39)IPR001251: Cellular retinaldehyde-binding/triple function, C-terminal
45 (58)1 (1671)1 (1736)IPR005189: Focal adhesion targeting region
44 (59)28 (54)61 (30)IPR002018: Carboxylesterase, type BMolecular Function: serine esterase activity (GO:0004759)
44 (60)5 (470)16 (169)IPR006026: Peptidase, metallopeptidasesBiological Process: proteolysis (GO:0006508), Molecular Function: metallopeptidase activity (GO:0008237)
44 (61) ()1 (1966)IPR007577: Glycosyltransferase sugar-binding region containing DXD motif
44 (62)2 (1240)2 (1327)IPR013662: RyR and IP3R Homology associated
43 (63)18 (110)23 (109)IPR013216: Methyltransferase type 11
42 (64)39 (35)46 (42)IPR006076: FAD dependent oxidoreductaseBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
41 (65)15 (129)29 (75)IPR000832: GPCR, family 2, secretin-likeMolecular Function: G-protein coupled receptor activity (GO:0004930), Cellular Component: membrane (GO:0016020)
40 (66)29 (50)34 (64)IPR001628: Nuclear hormone receptor, DNA-bindingMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355), Molecular Function: zinc ion binding (GO:0008270), Molecular Function: sequence-specific DNA binding (GO:0043565)
40 (67)9 (260)14 (201)IPR008191: Maternal tudor protein
39 (68)16 (115)19 (128)IPR000330: SNF2-relatedMolecular Function: DNA binding (GO:0003677), Molecular Function: ATP binding (GO:0005524)
39 (69)23 (70)22 (111)IPR001394: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2Molecular Function: ubiquitin thiolesterase activity (GO:0004221), Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511)
39 (70)15 (130)17 (152)IPR002999: TudorMolecular Function: nucleic acid binding (GO:0003676)
38 (71)28 (51)34 (63)IPR000626: UbiquitinBiological Process: protein modification (GO:0006464)
38 (72)17 (114)21 (120)IPR013217: Methyltransferase type 12
37 (73)1 (1636)6 (469)IPR004875: CENP-B proteinMolecular Function: nucleic acid binding (GO:0003676), Cellular Component: nucleus (GO:0005634)
37 (74)20 (91)28 (85)IPR006652: Kelch repeat
36 (75)11 (182)17 (148)IPR000834: Peptidase M14, carboxypeptidase AMolecular Function: carboxypeptidase A activity (GO:0004182), Biological Process: proteolysis (GO:0006508)
36 (76)2 (935)3 (771)IPR001506: Peptidase M12A, astacinBiological Process: proteolysis (GO:0006508), Molecular Function: astacin activity (GO:0008533)
35 (77)7 (299)6 (430)IPR000164: Histone H3Cellular Component: nucleosome (GO:0000786), Molecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: nucleosome assembly (GO:0006334), Biological Process: chromosome organization and biogenesis (sensu Eukaryota) (GO:0007001)
35 (78)28 (52)37 (54)IPR001623: Heat shock protein DnaJ, N-terminalMolecular Function: heat shock protein binding (GO:0031072)
35 (79)10 (215)20 (123)IPR002035: von Willebrand factor, type A
35 (80)8 (279)7 (389)IPR002223: Proteinase inhibitor I2, Kunitz metazoaMolecular Function: serine-type endopeptidase inhibitor activity (GO:0004867)
35 (81)37 (37)37 (55)IPR013027: FAD-dependent pyridine nucleotide-disulphide oxidoreductase
34 (82)23 (68)21 (117)IPR000225: Armadillo
34 (83)4 (518)5 (497)IPR000782: Beta-Ig-H3/fasciclinBiological Process: cell adhesion (GO:0007155)
33 (84)8 (267)13 (206)IPR000772: Ricin B lectin
33 (85)12 (165)28 (82)IPR000953: ChromoCellular Component: chromatin (GO:0000785), Molecular Function: chromatin binding (GO:0003682), Cellular Component: nucleus (GO:0005634), Biological Process: chromatin assembly or disassembly (GO:0006333)
33 (86)15 (133)17 (153)IPR004841: Amino acid permease-associated regionBiological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
32 (87)20 (87)24 (103)IPR001054: Adenylyl cyclase class-3/4/guanylyl cyclaseBiological Process: intracellular signaling cascade (GO:0007242), Biological Process: cyclic nucleotide biosynthetic process (GO:0009190), Molecular Function: phosphorus-oxygen lyase activity (GO:0016849)
32 (88)34 (40)38 (53)IPR001993: Mitochondrial substrate carrierMolecular Function: binding (GO:0005488), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
32 (89)26 (60)26 (95)IPR006202: Neurotransmitter-gated ion-channel ligand-bindingMolecular Function: extracellular ligand-gated ion channel activity (GO:0005230), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
31 (90)15 (128)16 (157)IPR000175: Sodium:neurotransmitter symporterMolecular Function: neurotransmitter:sodium symporter activity (GO:0005328), Cellular Component: integral to plasma membrane (GO:0005887), Biological Process: neurotransmitter transport (GO:0006836), Cellular Component: membrane (GO:0016020)
31 (91)4 (524)5 (502)IPR000999: Ribonuclease IIIMolecular Function: RNA binding (GO:0003723), Molecular Function: ribonuclease III activity (GO:0004525), Biological Process: RNA processing (GO:0006396)
31 (92)29 (49)36 (56)IPR001214: SETCellular Component: nucleus (GO:0005634)
31 (93)20 (89)26 (94)IPR001487: Bromodomain
31 (94)18 (104)43 (47)IPR001509: NAD-dependent epimerase/dehydrataseMolecular Function: catalytic activity (GO:0003824), Biological Process: cellular metabolic process (GO:0044237), Molecular Function: coenzyme binding (GO:0050662)
31 (95)27 (56)29 (76)IPR001715: Calponin-like actin-binding
31 (96)18 (105)25 (98)IPR002126: CadherinMolecular Function: calcium ion binding (GO:0005509), Biological Process: homophilic cell adhesion (GO:0007156), Cellular Component: membrane (GO:0016020)
31 (97)18 (108)25 (100)IPR011498: Kelch
31 (98)20 (94)35 (60)IPR013120: Male sterility C-terminal
31 (99)16 (126)18 (146)IPR013525: ABC-2 type transporter
30 (100)29 (46)28 (79)IPR000219: DHMolecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089), Cellular Component: intracellular (GO:0005622), Biological Process: regulation of Rho protein signal transduction (GO:0035023)
30 (101)26 (57)27 (87)IPR000299: Band 4.1Cellular Component: cytoskeleton (GO:0005856)
30 (102)9 (248)7 (402)IPR003594: ATP-binding region, ATPase-likeMolecular Function: ATP binding (GO:0005524)
30 (103)9 (249)7 (403)IPR003609: Apple-like
29 (104)24 (61)23 (105)IPR000195: RabGAP/TBCMolecular Function: Rab GTPase activator activity (GO:0005097), Cellular Component: intracellular (GO:0005622), Biological Process: regulation of Rab GTPase activity (GO:0032313)
29 (105)14 (141)15 (174)IPR000569: HECTMolecular Function: ubiquitin-protein ligase activity (GO:0004842), Cellular Component: intracellular (GO:0005622), Biological Process: protein modification (GO:0006464), Biological Process: ubiquitin cycle (GO:0006512)
29 (106)7 (307)10 (261)IPR000863: SulfotransferaseMolecular Function: sulfotransferase activity (GO:0008146)
29 (107)14 (143)18 (138)IPR001507: Endoglin/CD105 antigen
29 (108)4 (548)1 (1485)IPR001951: Histone H4Cellular Component: nucleosome (GO:0000786), Molecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: nucleosome assembly (GO:0006334), Biological Process: chromosome organization and biogenesis (sensu Eukaryota) (GO:0007001)
29 (109)32 (43)44 (44)IPR004089: Bacterial chemotaxis sensory transducerMolecular Function: signal transducer activity (GO:0004871), Biological Process: chemotaxis (GO:0006935), Biological Process: signal transduction (GO:0007165), Cellular Component: membrane (GO:0016020)
29 (110)6 (391)2 (1104)IPR004823: TATA box binding protein associated factor (TAF)Cellular Component: nucleus (GO:0005634), Biological Process: transcription initiation (GO:0006352), Molecular Function: transcription initiation factor activity (GO:0016986)
29 (111)8 (289)36 (58)IPR006612: Zinc finger, C2CH-typeMolecular Function: nucleic acid binding (GO:0003676)
29 (112)23 (71)22 (115)IPR011510: Sterile alpha motif homology 2
29 (113)35 (39)32 (72)IPR011704: ATPase associated with various cellular activities, AAA-5Molecular Function: ATP binding (GO:0005524), Molecular Function: ATPase activity (GO:0016887)
29 (114)24 (66)26 (96)IPR013099: Ion transport 2
28 (115)2 (900)3 (750)IPR000885: Fibrillar collagen, C-terminalMolecular Function: extracellular matrix structural constituent (GO:0005201), Cellular Component: collagen (GO:0005581)
28 (116)24 (65)27 (88)IPR001828: Extracellular ligand-binding receptor
28 (117)10 (214)18 (139)IPR001930: Peptidase M1, membrane alanine aminopeptidaseMolecular Function: membrane alanyl aminopeptidase activity (GO:0004179), Biological Process: proteolysis (GO:0006508)
28 (118)6 (375)7 (387)IPR002119: Histone H2ACellular Component: nucleosome (GO:0000786), Molecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: nucleosome assembly (GO:0006334), Biological Process: chromosome organization and biogenesis (sensu Eukaryota) (GO:0007001)
28 (119)11 (190)11 (246)IPR003958: Transcription factor CBF/NF-Y/archaeal histoneCellular Component: intracellular (GO:0005622), Molecular Function: sequence-specific DNA binding (GO:0043565)
28 (120)19 (101)33 (69)IPR013253: Kinetochore Spc7
27 (121)4 (562)6 (459)IPR002861: Reeler region
27 (122)9 (254)12 (230)IPR005123: 2OG-Fe(II) oxygenase
27 (123)19 (99)22 (114)IPR005834: Haloacid dehalogenase-like hydrolaseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolic process (GO:0008152)
27 (124)7 (346)8 (358)IPR009038: GOLD
27 (125)16 (124)19 (136)IPR013234: PIGA, GPI anchor biosynthesis
26 (126)7 (296)14 (183)IPR000033: Low-density lipoprotein receptor, YWTD repeatCellular Component: membrane (GO:0016020)
26 (127)6 (355)7 (368)IPR000348: emp24/gp25L/p24Biological Process: transport (GO:0006810), Cellular Component: integral to membrane (GO:0016021)
26 (128)11 (180)15 (173)IPR000436: Sushi/SCR/CCP
26 (129)26 (58)28 (80)IPR000608: Ubiquitin-conjugating enzyme, E2Molecular Function: ubiquitin-protein ligase activity (GO:0004842), Biological Process: protein modification (GO:0006464), Biological Process: ubiquitin cycle (GO:0006512)
26 (130)7 (302)14 (187)IPR000637: HMG-I and HMG-Y, DNA-binding
26 (131)22 (76)25 (99)IPR006029: Neurotransmitter-gated ion-channel transmembrane regionBiological Process: ion transport (GO:0006811), Cellular Component: membrane (GO:0016020), Molecular Function: neurotransmitter receptor activity (GO:0030594)
25 (132)29 (47)38 (52)IPR000483: Cysteine-rich flanking region, C-terminal
25 (133)21 (78)19 (129)IPR000536: Nuclear hormone receptor, ligand-binding, coreMolecular Function: transcription factor activity (GO:0003700), Molecular Function: steroid hormone receptor activity (GO:0003707), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
25 (134)8 (284)8 (346)IPR003890: Initiation factor eIF-4 gamma, middleMolecular Function: RNA binding (GO:0003723)
24 (135)12 (170)29 (77)IPR002213: UDP-glucuronosyl/UDP-glucosyltransferaseBiological Process: metabolic process (GO:0008152), Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758)
24 (136)21 (84)28 (84)IPR004843: MetallophosphoesteraseMolecular Function: hydrolase activity (GO:0016787)
24 (137)33 (42)55 (37)IPR013138: Zinc finger TFIIS-type 2Molecular Function: RNA polymerase II transcription factor activity (GO:0003702), Molecular Function: zinc ion binding (GO:0008270), Biological Process: regulation of transcription (GO:0045449)
23 (138)19 (96)14 (185)IPR000182: GCN5-related N-acetyltransferaseMolecular Function: N-acetyltransferase activity (GO:0008080), Biological Process: metabolic process (GO:0008152)
23 (139)11 (184)8 (328)IPR001148: Carbonic anhydrase, eukaryoticMolecular Function: carbonate dehydratase activity (GO:0004089), Biological Process: one-carbon compound metabolic process (GO:0006730), Molecular Function: zinc ion binding (GO:0008270)
23 (140)19 (98)17 (149)IPR001609: Myosin head, motor regionMolecular Function: motor activity (GO:0003774), Molecular Function: ATP binding (GO:0005524), Cellular Component: myosin complex (GO:0016459)
23 (141)3 (806)3 (866)IPR007081: RNA polymerase Rpb1, domain 5Molecular Function: DNA binding (GO:0003677), Molecular Function: DNA-directed RNA polymerase activity (GO:0003899), Biological Process: transcription (GO:0006350)
22 (142)24 (62)23 (106)IPR000727: Target SNARE coiled-coil region
22 (143)24 (63)26 (92)IPR000884: Thrombospondin, type I
22 (144)12 (166)20 (121)IPR001007: von Willebrand factor, type C
22 (145)6 (365)22 (110)IPR001283: Allergen V5/Tpx-1 relatedCellular Component: extracellular region (GO:0005576)
22 (146)7 (319)5 (511)IPR001619: Sec1-like proteinBiological Process: vesicle docking during exocytosis (GO:0006904), Biological Process: vesicle-mediated transport (GO:0016192)
22 (147)6 (370)7 (382)IPR001747: Lipid transport protein, N-terminalMolecular Function: lipid transporter activity (GO:0005319), Biological Process: lipid transport (GO:0006869)
22 (148)24 (64)24 (104)IPR001791: Laminin G
22 (149)7 (322)7 (384)IPR001846: von Willebrand factor, type D
22 (150)21 (81)16 (167)IPR003597: Immunoglobulin C1-set
22 (151)24 (67)27 (90)IPR013766: Thioredoxin domain
22 (152)15 (138)27 (91)IPR013818: Lipase, N-terminal
22 (153)11 (202)31 (73)IPR013968: KR
21 (154)29 (45)34 (61)IPR000048: IQ calmodulin-binding region
21 (155)29 (48)33 (68)IPR000980: SH2 motifBiological Process: intracellular signaling cascade (GO:0007242)
21 (156)23 (69)26 (93)IPR001202: WW/Rsp5/WWP
21 (157)5 (431)8 (333)IPR001309: Caspase, p20 subunitBiological Process: proteolysis (GO:0006508), Molecular Function: caspase activity (GO:0030693)
21 (158)14 (142)16 (163)IPR001357: BRCTCellular Component: intracellular (GO:0005622)
21 (159)8 (285)23 (107)IPR004262: Male sterility
21 (160)1 (2187)1 (2224)IPR010655: Pre-mRNA cleavage complex II Clp1
21 (161)23 (72)20 (126)IPR012680: Laminin G, subdomain 2
21 (162)5 (495)18 (145)IPR013201: Proteinase inhibitor I29, cathepsin propeptide
21 (163)10 (226)10 (278)IPR013520: Exonuclease, RNase T and DNA polymerase III
21 (164)5 (498)22 (116)IPR014044: SCP-like extracellular
20 (165)22 (73)27 (86)IPR000172: Glucose-methanol-choline oxidoreductase, N-terminalBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
20 (166)13 (150)14 (186)IPR000342: Regulator of G protein signallingMolecular Function: signal transducer activity (GO:0004871)
20 (167)16 (116)12 (222)IPR000467: D111/G-patchMolecular Function: nucleic acid binding (GO:0003676), Cellular Component: intracellular (GO:0005622)
20 (168)17 (112)21 (119)IPR003953: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminalBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
20 (169)17 (113)15 (180)IPR006552: VWC out
20 (170)11 (197)12 (232)IPR008250: E1-E2 ATPase-associated regionMolecular Function: ATP binding (GO:0005524), Cellular Component: membrane (GO:0016020), Molecular Function: hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances (GO:0016820)
20 (171)19 (102)44 (46)IPR013604: 7TM chemoreceptor
19 (172)10 (205)10 (258)IPR000192: Aminotransferase, class VBiological Process: metabolic process (GO:0008152), Molecular Function: transaminase activity (GO:0008483)
19 (173)12 (164)13 (205)IPR000403: Phosphatidylinositol 3- and 4-kinase, catalyticMolecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773)
19 (174)16 (118)17 (147)IPR000795: Protein synthesis factor, GTP-bindingMolecular Function: GTPase activity (GO:0003924), Molecular Function: GTP binding (GO:0005525)
19 (175)1 (1360)1 (1421)IPR001241: DNA topoisomerase, type IIA, subunit B or N-terminalMolecular Function: DNA binding (GO:0003677), Molecular Function: DNA topoisomerase (ATP-hydrolyzing) activity (GO:0003918), Molecular Function: ATP binding (GO:0005524), Cellular Component: chromosome (GO:0005694), Biological Process: DNA topological change (GO:0006265)
19 (176)7 (311)7 (377)IPR001247: ExoribonucleaseMolecular Function: 3'-5'-exoribonuclease activity (GO:0000175), Molecular Function: RNA binding (GO:0003723), Biological Process: RNA processing (GO:0006396)
19 (177)8 (278)28 (83)IPR001873: Na+ channel, amiloride-sensitiveMolecular Function: sodium channel activity (GO:0005272), Biological Process: sodium ion transport (GO:0006814), Cellular Component: membrane (GO:0016020)
19 (178)20 (90)19 (132)IPR002917: GTP-binding protein, HSR1-relatedMolecular Function: GTP binding (GO:0005525), Cellular Component: intracellular (GO:0005622)
19 (179)21 (82)22 (112)IPR004000: Actin/actin-likeMolecular Function: protein binding (GO:0005515)
19 (180)22 (75)45 (43)IPR004704: Phosphotransferase system, mannose/fructose/sorbose family IID componentBiological Process: phosphoenolpyruvate-dependent sugar phosphotransferase system (GO:0009401), Cellular Component: integral to membrane (GO:0016021)
19 (181)3 (786)3 (846)IPR006592: RNA polymerase I, subunit A, N-terminalMolecular Function: DNA binding (GO:0003677), Molecular Function: DNA-directed RNA polymerase activity (GO:0003899), Biological Process: transcription (GO:0006350)
19 (182)3 (805)3 (865)IPR007080: RNA polymerase Rpb1, domain 1Molecular Function: DNA binding (GO:0003677), Molecular Function: DNA-directed RNA polymerase activity (GO:0003899), Biological Process: transcription (GO:0006350)
19 (183)11 (198)17 (154)IPR008753: Peptidase M13Biological Process: proteolysis (GO:0006508), Molecular Function: metallopeptidase activity (GO:0008237)
19 (184)8 (292)8 (359)IPR011021: Arrestin, N-terminal
19 (185)8 (293)8 (360)IPR011022: Arrestin, C-terminal
19 (186)16 (123)43 (49)IPR011527: ABC transporter, transmembrane region, type 1Molecular Function: ATP binding (GO:0005524), Biological Process: transport (GO:0006810), Cellular Component: integral to membrane (GO:0016021), Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626)
19 (187)5 (490)8 (361)IPR011600: Peptidase C14, caspase catalyticBiological Process: proteolysis (GO:0006508), Molecular Function: caspase activity (GO:0030693)
19 (188)20 (93)18 (144)IPR012679: Laminin G, subdomain 1
19 (189)11 (199)23 (108)IPR013149: Alcohol dehydrogenase, zinc-binding
19 (190)12 (176)13 (220)IPR013154: Alcohol dehydrogenase GroES-like
18 (191)9 (230)16 (161)IPR000718: Peptidase M13, neprilysinMolecular Function: neprilysin activity (GO:0004245), Biological Process: proteolysis (GO:0006508), Cellular Component: membrane (GO:0016020)
18 (192)18 (103)19 (130)IPR001163: Like-Sm ribonucleoprotein, coreBiological Process: mRNA metabolic process (GO:0016071), Cellular Component: ribonucleoprotein complex (GO:0030529)
18 (193)21 (79)21 (118)IPR001683: Phox-likeMolecular Function: protein binding (GO:0005515), Biological Process: cell communication (GO:0007154), Molecular Function: phosphoinositide binding (GO:0035091)
18 (194)3 (718)4 (653)IPR002928: Myosin tailMolecular Function: motor activity (GO:0003774), Cellular Component: myosin complex (GO:0016459)
18 (195)14 (146)13 (217)IPR006594: Lissencephaly type-1-like homology motif
18 (196)15 (137)15 (181)IPR006671: Cyclin, N-terminalBiological Process: regulation of progression through cell cycle (GO:0000074)
18 (197)3 (804)3 (864)IPR007066: RNA polymerase Rpb1, domain 3Molecular Function: DNA binding (GO:0003677), Molecular Function: DNA-directed RNA polymerase activity (GO:0003899), Biological Process: transcription (GO:0006350)
18 (198)3 (820)1 (1974)IPR007652: Alpha 1,4-glycosyltransferase conserved regionCellular Component: Golgi stack (GO:0005795), Molecular Function: galactosyltransferase activity (GO:0008378)
17 (199)11 (177)14 (184)IPR000058: Zinc finger, AN1-typeMolecular Function: zinc ion binding (GO:0008270)
17 (200)4 (514)4 (604)IPR000558: Histone H2BCellular Component: nucleosome (GO:0000786), Molecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: nucleosome assembly (GO:0006334), Biological Process: chromosome organization and biogenesis (sensu Eukaryota) (GO:0007001)
17 (201)16 (117)16 (160)IPR000717: Proteasome component region PCI
17 (202)3 (656)3 (746)IPR000722: RNA polymerase, alpha subunitMolecular Function: DNA binding (GO:0003677), Molecular Function: DNA-directed RNA polymerase activity (GO:0003899), Cellular Component: nucleus (GO:0005634), Biological Process: transcription (GO:0006350)
17 (203)11 (183)9 (287)IPR000909: Phosphatidylinositol-specific phospholipase C, X regionMolecular Function: phospholipase C activity (GO:0004629), Biological Process: signal transduction (GO:0007165), Biological Process: intracellular signaling cascade (GO:0007242)
17 (204)16 (120)15 (178)IPR002130: Peptidyl-prolyl cis-trans isomerase, cyclophilin-typeBiological Process: protein folding (GO:0006457)
17 (205)3 (699)7 (388)IPR002181: Fibrinogen, alpha/beta/gamma chain, C-terminal globularMolecular Function: receptor binding (GO:0005102), Biological Process: signal transduction (GO:0007165)
17 (206)9 (256)14 (198)IPR006091: Acyl-CoA dehydrogenase/oxidase, central regionMolecular Function: acyl-CoA dehydrogenase activity (GO:0003995), Biological Process: electron transport (GO:0006118)
17 (207)3 (807)3 (867)IPR007083: RNA polymerase Rpb1, domain 4Molecular Function: DNA binding (GO:0003677), Molecular Function: DNA-directed RNA polymerase activity (GO:0003899), Biological Process: transcription (GO:0006350)
17 (208)20 (92)29 (78)IPR007867: Glucose-methanol-choline oxidoreductase, C-terminalMolecular Function: oxidoreductase activity, acting on CH-OH group of donors (GO:0016614), Molecular Function: FAD binding (GO:0050660)
16 (209)10 (203)15 (172)IPR000086: NUDIX hydrolaseMolecular Function: hydrolase activity (GO:0016787)
16 (210)21 (77)34 (62)IPR000301: CD9/CD37/CD63 antigenCellular Component: integral to membrane (GO:0016021)
16 (211)13 (153)15 (175)IPR001353: 20S proteasome, A and B subunitsMolecular Function: threonine endopeptidase activity (GO:0004298), Cellular Component: proteasome core complex (sensu Eukaryota) (GO:0005839), Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511)
16 (212)9 (237)20 (122)IPR001395: Aldo/keto reductaseMolecular Function: oxidoreductase activity (GO:0016491)
16 (213)10 (210)13 (208)IPR001494: Importin-beta, N-terminalBiological Process: protein import into nucleus, docking (GO:0000059), Cellular Component: nucleus (GO:0005634), Cellular Component: nuclear pore (GO:0005643), Cellular Component: cytoplasm (GO:0005737), Biological Process: intracellular protein transport (GO:0006886), Molecular Function: protein transporter activity (GO:0008565)
16 (214)16 (119)19 (131)IPR001774: Delta/Serrate/lag-2 (DSL) proteinBiological Process: cell communication (GO:0007154), Cellular Component: membrane (GO:0016020)
16 (215)5 (442)9 (297)IPR002398: Peptidase C14, caspase precursor p45Biological Process: proteolysis (GO:0006508), Molecular Function: caspase activity (GO:0030693)
16 (216)10 (221)14 (197)IPR003607: Metal-dependent phosphohydrolase, HD regionMolecular Function: catalytic activity (GO:0003824)
16 (217)8 (287)8 (351)IPR005018: DOMON related
16 (218)18 (107)34 (65)IPR010409: GAGA binding-like
16 (219)16 (125)25 (101)IPR013256: Chromatin SPT2
15 (220)10 (206)12 (221)IPR000337: GPCR, family 3, metabotropic glutamate receptor-likeMolecular Function: metabotropic glutamate, GABA-B-like receptor activity (GO:0008067), Cellular Component: membrane (GO:0016020)
15 (221)2 (888)3 (740)IPR000412: ABC-2Molecular Function: ATP binding (GO:0005524), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020), Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626)
15 (222)3 (651)4 (605)IPR000615: Bestrophin
15 (223)8 (271)9 (289)IPR000994: Peptidase M24, catalytic coreBiological Process: proteolysis (GO:0006508), Molecular Function: metalloexopeptidase activity (GO:0008235)
15 (224)9 (233)10 (265)IPR001164: Arf GTPase activating proteinBiological Process: regulation of GTPase activity (GO:0043087)
15 (225)6 (366)8 (336)IPR001433: Oxidoreductase FAD/NAD(P)-bindingBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
15 (226)2 (944)8 (338)IPR001604: DNA/RNA non-specific endonucleaseMolecular Function: nucleic acid binding (GO:0003676), Molecular Function: endonuclease activity (GO:0004519)
15 (227)14 (145)14 (193)IPR002076: GNS1/SUR4 membrane proteinCellular Component: integral to membrane (GO:0016021)
15 (228)9 (242)13 (210)IPR002086: Aldehyde dehydrogenaseBiological Process: metabolic process (GO:0008152), Molecular Function: oxidoreductase activity (GO:0016491)
15 (229)13 (157)20 (124)IPR002225: 3-beta hydroxysteroid dehydrogenase/isomeraseMolecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854), Biological Process: steroid biosynthetic process (GO:0006694)
15 (230)13 (160)12 (229)IPR004839: Aminotransferase, class I and IIBiological Process: biosynthetic process (GO:0009058), Molecular Function: transferase activity, transferring nitrogenous groups (GO:0016769)
15 (231)15 (134)13 (215)IPR006195: Aminoacyl-transfer RNA synthetase, class IIMolecular Function: aminoacyl-tRNA ligase activity (GO:0004812), Molecular Function: ATP binding (GO:0005524), Biological Process: tRNA aminoacylation for protein translation (GO:0006418)
15 (232)4 (611)19 (133)IPR006693: AB-hydrolase associated lipase regionBiological Process: lipid metabolic process (GO:0006629), Molecular Function: carboxylic ester hydrolase activity (GO:0016789)
14 (233)14 (139)16 (156)IPR000014: PASMolecular Function: signal transducer activity (GO:0004871), Biological Process: signal transduction (GO:0007165)
14 (234)17 (111)19 (127)IPR000159: RABiological Process: signal transduction (GO:0007165)
14 (235)7 (304)8 (324)IPR000644: Cystathionine-beta-synthase
14 (236)13 (152)24 (102)IPR000679: Zinc finger, GATA-typeMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355), Molecular Function: zinc ion binding (GO:0008270), Molecular Function: sequence-specific DNA binding (GO:0043565)
14 (237)4 (523)2 (971)IPR000998: MAMCellular Component: membrane (GO:0016020)
14 (238)3 (682)5 (507)IPR001424: Superoxide dismutase, copper/zinc bindingMolecular Function: copper, zinc superoxide dismutase activity (GO:0004785), Biological Process: superoxide metabolic process (GO:0006801), Molecular Function: metal ion binding (GO:0046872)
14 (239)6 (369)5 (513)IPR001711: Phosphatidylinositol-specific phospholipase C, Y domainMolecular Function: phosphoinositide phospholipase C activity (GO:0004435), Biological Process: lipid metabolic process (GO:0006629), Biological Process: signal transduction (GO:0007165), Biological Process: intracellular signaling cascade (GO:0007242)
14 (240)10 (213)11 (239)IPR001879: Hormone receptor, extracellularMolecular Function: G-protein coupled receptor activity (GO:0004930), Cellular Component: membrane (GO:0016020)
14 (241)10 (219)10 (268)IPR002423: Chaperonin Cpn60/TCP-1Molecular Function: protein binding (GO:0005515), Molecular Function: ATP binding (GO:0005524), Biological Process: cellular protein metabolic process (GO:0044267)
14 (242)4 (576)4 (667)IPR003653: Peptidase C48, SUMO/Sentrin/Ubl1Biological Process: proteolysis (GO:0006508), Molecular Function: cysteine-type peptidase activity (GO:0008234)
14 (243)12 (172)13 (214)IPR003877: SPla/RYanodine receptor SPRY
14 (244)4 (587)5 (545)IPR004878: Protein of unknown function DUF270
14 (245)9 (261)9 (315)IPR011547: Sulphate transporterMolecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: integral to membrane (GO:0016021)
13 (246)10 (204)13 (203)IPR000118: Granulin
13 (247)11 (179)10 (259)IPR000313: PWWP
13 (248)12 (167)11 (235)IPR001060: Cdc15/Fes/CIP4
13 (249)2 (930)1 (1427)IPR001339: mRNA capping enzymeMolecular Function: mRNA guanylyltransferase activity (GO:0004484), Biological Process: mRNA capping (GO:0006370), Biological Process: mRNA processing (GO:0006397)
13 (250)7 (313)11 (237)IPR001373: CullinBiological Process: cell cycle (GO:0007049)
13 (251)4 (537)7 (381)IPR001464: AnnexinMolecular Function: calcium ion binding (GO:0005509), Molecular Function: calcium-dependent phospholipid binding (GO:0005544)
13 (252)12 (169)12 (223)IPR001594: Zinc finger, DHHC-typeMolecular Function: zinc ion binding (GO:0008270)
13 (253)13 (154)14 (192)IPR001638: Bacterial extracellular solute-binding protein, family 3Molecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: outer membrane-bounded periplasmic space (GO:0030288)
13 (254)10 (212)12 (224)IPR001753: Enoyl-CoA hydratase/isomeraseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolic process (GO:0008152)
13 (255)8 (283)9 (301)IPR003689: Zinc/iron permeaseCellular Component: membrane (GO:0016020), Biological Process: metal ion transport (GO:0030001), Molecular Function: metal ion transporter activity (GO:0046873)
13 (256)3 (732)3 (811)IPR003859: Metazoa galactosyltransferaseBiological Process: carbohydrate metabolic process (GO:0005975), Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757)
13 (257)7 (337)9 (304)IPR004365: Nucleic acid binding, OB-fold, tRNA/helicase-typeMolecular Function: nucleic acid binding (GO:0003676)
13 (258)15 (135)9 (309)IPR006212: Furin-like repeat
13 (259)10 (224)13 (219)IPR008145: Guanylate kinase/L-type calcium channel region
13 (260)9 (262)11 (256)IPR011703: ATPase associated with various cellular activities, AAA-3Molecular Function: ATP binding (GO:0005524), Molecular Function: ATPase activity (GO:0016887)
13 (261)4 (636)5 (581)IPR013121: Ferric reductase, NAD binding
13 (262)16 (127)14 (202)IPR013602: Dynein heavy chain, N-terminal region 2
13 (263) ()1 (2376)IPR013642: Chloride channel calcium-activated
12 (264)1 (1257)2 (932)IPR000010: Proteinase inhibitor I25, cystatinMolecular Function: cysteine protease inhibitor activity (GO:0004869)
12 (265)4 (505)6 (432)IPR000286: Histone deacetylase superfamily
12 (266)8 (272)8 (327)IPR001019: Guanine nucleotide binding protein (G-protein), alpha subunitMolecular Function: signal transducer activity (GO:0004871), Biological Process: G-protein coupled receptor protein signaling pathway (GO:0007186), Molecular Function: guanyl nucleotide binding (GO:0019001)
12 (267)8 (273)10 (264)IPR001107: Band 7 protein
12 (268)7 (310)8 (329)IPR001179: Peptidyl-prolyl cis-trans isomerase, FKBP-typeBiological Process: protein folding (GO:0006457)
12 (269)5 (430)3 (763)IPR001212: Somatomedin B
12 (270)9 (235)14 (190)IPR001258: NHL repeat
12 (271)9 (238)15 (176)IPR001496: SOCS protein, C-terminalBiological Process: intracellular signaling cascade (GO:0007242)
12 (272)6 (367)10 (266)IPR001540: Glycoside hydrolase, family 20Molecular Function: beta-N-acetylhexosaminidase activity (GO:0004563), Biological Process: carbohydrate metabolic process (GO:0005975)
12 (273)14 (144)11 (238)IPR001590: Peptidase M12B, ADAM/reprolysinMolecular Function: metalloendopeptidase activity (GO:0004222), Biological Process: proteolysis (GO:0006508)
12 (274)13 (155)16 (164)IPR001734: Na+/solute symporterMolecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
12 (275)2 (952)13 (209)IPR001818: Peptidase M10A and M12B, matrixin and adamalysinMolecular Function: metalloendopeptidase activity (GO:0004222), Cellular Component: proteinaceous extracellular matrix (GO:0005578), Biological Process: proteolysis (GO:0006508)
12 (276)5 (436)6 (452)IPR002108: Actin-binding, cofilin/tropomyosin typeMolecular Function: actin binding (GO:0003779), Cellular Component: intracellular (GO:0005622)
12 (277)8 (280)16 (166)IPR002937: Amine oxidaseBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
12 (278)15 (131)12 (227)IPR003008: Tubulin/FtsZ, GTPase
12 (279)18 (106)18 (140)IPR003126: Zinc finger, N-recogninMolecular Function: ubiquitin-protein ligase activity (GO:0004842), Biological Process: ubiquitin cycle (GO:0006512), Molecular Function: zinc ion binding (GO:0008270)
12 (280)13 (159)13 (213)IPR003649: B-box, C-terminalCellular Component: intracellular (GO:0005622)
12 (281)16 (121)12 (228)IPR004148: BARMolecular Function: protein binding (GO:0005515), Cellular Component: cytoplasm (GO:0005737)
12 (282)3 (754)8 (349)IPR004302: Chitin-binding, domain 3Cellular Component: viral capsid (GO:0019028)
12 (283)8 (288)9 (308)IPR005817: Wnt superfamilyMolecular Function: signal transducer activity (GO:0004871), Cellular Component: extracellular region (GO:0005576), Biological Process: frizzled-2 signaling pathway (GO:0007223), Biological Process: multicellular organismal development (GO:0007275)
12 (284)1 (1723)2 (1146)IPR006088: Sterol desaturaseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolic process (GO:0008152)
12 (285)3 (787)6 (475)IPR006600: Centromere protein B, DNA-binding region
12 (286)11 (195)27 (89)IPR006604: Disulphide knot CLIP
12 (287)11 (196)12 (231)IPR006935: Type III restriction enzyme, res subunitMolecular Function: ATP binding (GO:0005524)
12 (288)14 (147)14 (200)IPR007502: Helicase-associated regionMolecular Function: helicase activity (GO:0004386)
12 (289)14 (149)11 (255)IPR008280: Tubulin/FtsZ, C-terminalMolecular Function: GTPase activity (GO:0003924), Molecular Function: GTP binding (GO:0005525), Cellular Component: protein complex (GO:0043234), Biological Process: protein polymerization (GO:0051258)
12 (290)13 (161)15 (182)IPR011497: Protease inhibitor, Kazal-type
12 (291)3 (856)3 (907)IPR011644: Heme NO bindingMolecular Function: guanylate cyclase activity (GO:0004383), Biological Process: cGMP biosynthetic process (GO:0006182), Molecular Function: heme binding (GO:0020037)
12 (292)13 (162)16 (170)IPR011705: BTB/Kelch-associated
12 (293)13 (163)19 (135)IPR013057: Amino acid transporter, transmembrane
11 (294)8 (265)7 (365)IPR000089: Biotin/lipoyl attachment
11 (295)11 (178)13 (204)IPR000157: Toll-Interleukin receptorMolecular Function: transmembrane receptor activity (GO:0004888), Cellular Component: membrane (GO:0016020)
11 (296)4 (516)5 (493)IPR000648: Oxysterol-binding proteinBiological Process: steroid metabolic process (GO:0008202)
11 (297)11 (181)14 (188)IPR000687: RIO kinaseMolecular Function: protein serine/threonine kinase activity (GO:0004674), Molecular Function: ATP binding (GO:0005524)
11 (298)2 (896)2 (954)IPR000699: Intracellular calcium-release channelMolecular Function: calcium channel activity (GO:0005262), Biological Process: calcium ion transport (GO:0006816), Cellular Component: membrane (GO:0016020)
11 (299)9 (232)7 (374)IPR001012: UBX
11 (300)11 (185)11 (236)IPR001173: Glycosyl transferase, family 2
11 (301)8 (274)8 (330)IPR001208: MCMMolecular Function: DNA binding (GO:0003677), Molecular Function: ATP binding (GO:0005524), Biological Process: DNA replication initiation (GO:0006270), Molecular Function: DNA-dependent ATPase activity (GO:0008094)
11 (302)11 (186)16 (162)IPR001275: DM DNA-bindingMolecular Function: DNA binding (GO:0003677), Molecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355), Biological Process: sex differentiation (GO:0007548)
11 (303)6 (371)9 (294)IPR001762: Disintegrin
11 (304)9 (241)12 (225)IPR001895: Guanine-nucleotide dissociation stimulator CDC25Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085), Cellular Component: intracellular (GO:0005622), Biological Process: small GTPase mediated signal transduction (GO:0007264)
11 (305)11 (188)12 (226)IPR001932: Protein phosphatase 2C-relatedMolecular Function: catalytic activity (GO:0003824)
11 (306)13 (156)10 (267)IPR002123: Phospholipid/glycerol acyltransferaseBiological Process: metabolic process (GO:0008152), Molecular Function: acyltransferase activity (GO:0008415)
11 (307)10 (217)13 (211)IPR002129: Pyridoxal-dependent decarboxylaseMolecular Function: carboxy-lyase activity (GO:0016831), Biological Process: carboxylic acid metabolic process (GO:0019752)
11 (308)5 (440)3 (785)IPR002205: DNA topoisomerase, type IIA, subunit A or C-terminalMolecular Function: DNA binding (GO:0003677), Molecular Function: DNA topoisomerase (ATP-hydrolyzing) activity (GO:0003918), Molecular Function: ATP binding (GO:0005524), Cellular Component: chromosome (GO:0005694), Biological Process: DNA metabolic process (GO:0006259), Biological Process: DNA topological change (GO:0006265)
11 (309)4 (557)8 (342)IPR002509: Polysaccharide deacetylaseBiological Process: carbohydrate metabolic process (GO:0005975), Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810)
11 (310)7 (326)7 (392)IPR002553: Adaptin, N-terminal
11 (311)6 (380)6 (460)IPR002938: Monooxygenase, FAD-bindingMolecular Function: monooxygenase activity (GO:0004497), Biological Process: electron transport (GO:0006118), Biological Process: aromatic compound metabolic process (GO:0006725)
11 (312)6 (383)7 (396)IPR003100: Argonaute and Dicer protein, PAZ
11 (313)4 (570)5 (531)IPR003165: Stem cell self-renewal protein Piwi
11 (314)10 (220)9 (300)IPR003395: SMC protein, N-terminalMolecular Function: ATP binding (GO:0005524), Cellular Component: chromosome (GO:0005694), Biological Process: DNA metabolic process (GO:0006259)
11 (315)12 (171)11 (244)IPR003613: U boxCellular Component: ubiquitin ligase complex (GO:0000151), Molecular Function: ubiquitin-protein ligase activity (GO:0004842), Biological Process: protein ubiquitination (GO:0016567)
11 (316)10 (222)11 (245)IPR003659: Plexin/semaphorin/integrinBiological Process: multicellular organismal development (GO:0007275)
11 (317)9 (252)9 (303)IPR003903: Ubiquitin interacting motif
11 (318)6 (387)7 (409)IPR004014: ATPase, P-type cation-transporter, N-terminalBiological Process: cation transport (GO:0006812), Molecular Function: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism (GO:0015662), Cellular Component: membrane (GO:0016020)
11 (319)5 (463)6 (472)IPR005113: uDENN
11 (320)5 (473)8 (352)IPR006153: Sodium/hydrogen exchangerBiological Process: regulation of pH (GO:0006885), Molecular Function: solute:hydrogen antiporter activity (GO:0015299), Cellular Component: integral to membrane (GO:0016021)
11 (321)11 (194)11 (250)IPR006586: ADAM, cysteine-rich
11 (322)9 (258)14 (199)IPR006631: Protein of unknown function DM4/12
11 (323)6 (400)11 (252)IPR007527: Zinc finger, SWIM-typeMolecular Function: zinc ion binding (GO:0008270)
11 (324)4 (624)2 (1253)IPR010256: Rh-like protein/ammonium transporter
11 (325)6 (413)8 (363)IPR013657: UAA transporter
10 (326)7 (295)8 (320)IPR000024: Frizzled CRD region
10 (327)3 (642)4 (591)IPR000101: Gamma-glutamyltranspeptidaseMolecular Function: gamma-glutamyltransferase activity (GO:0003840)
10 (328)6 (352)6 (431)IPR000209: Peptidase S8 and S53, subtilisin, kexin, sedolisinMolecular Function: subtilase activity (GO:0004289), Biological Process: proteolysis (GO:0006508)
10 (329)13 (151)16 (158)IPR000408: Regulator of chromosome condensation, RCC1
10 (330)10 (207)11 (234)IPR000555: Mov34/MPN/PAD-1
10 (331)9 (229)8 (323)IPR000594: UBA/THIF-type NAD/FAD binding foldMolecular Function: catalytic activity (GO:0003824)
10 (332)6 (360)9 (286)IPR000904: SEC7-likeMolecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086), Cellular Component: intracellular (GO:0005622), Biological Process: regulation of ARF protein signal transduction (GO:0032012)
10 (333)6 (362)7 (376)IPR001180: Citron-likeMolecular Function: small GTPase regulator activity (GO:0005083)
10 (334)6 (364)7 (378)IPR001279: Beta-lactamase-likeMolecular Function: hydrolase activity (GO:0016787)
10 (335)8 (275)7 (380)IPR001388: SynaptobrevinCellular Component: integral to membrane (GO:0016021), Biological Process: vesicle-mediated transport (GO:0016192)
10 (336)4 (544)6 (450)IPR001739: Methyl-CpG bindingMolecular Function: DNA binding (GO:0003677)
10 (337)8 (277)8 (341)IPR001763: Rhodanese-like
10 (338)9 (240)9 (295)IPR001839: Transforming growth factor betaMolecular Function: growth factor activity (GO:0008083)
10 (339)7 (324)6 (456)IPR002300: Aminoacyl-tRNA synthetase, class IaMolecular Function: aminoacyl-tRNA ligase activity (GO:0004812), Molecular Function: ATP binding (GO:0005524), Biological Process: tRNA aminoacylation for protein translation (GO:0006418)
10 (340)11 (189)15 (179)IPR002350: Proteinase inhibitor I1, Kazal
10 (341)9 (244)11 (241)IPR002895: Paramecium surface antigen
10 (342)5 (447)5 (525)IPR002931: Transglutaminase-like
10 (343)9 (250)7 (404)IPR003616: Post-SET zinc-binding regionCellular Component: nucleus (GO:0005634)
10 (344)11 (193)7 (413)IPR006560: AWS
10 (345)7 (342)7 (414)IPR006595: CTLH, C-terminal to LisH motif
10 (346)5 (485)6 (480)IPR007728: Pre-SET zinc-binding regionCellular Component: nucleus (GO:0005634), Molecular Function: zinc ion binding (GO:0008270), Biological Process: chromatin modification (GO:0016568), Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024)
10 (347)9 (259)8 (356)IPR008144: Guanylate kinase
10 (348)12 (175)12 (233)IPR011709: Domain of unknown function DUF1605
10 (349)2 (1224)3 (918)IPR013112: FAD-binding 8
10 (350)2 (1226)3 (919)IPR013130: Ferric reductase-like transmembrane component, N-terminalMolecular Function: iron ion binding (GO:0005506), Biological Process: electron transport (GO:0006118), Cellular Component: integral to membrane (GO:0016021), Molecular Function: oxidoreductase activity (GO:0016491), Molecular Function: FAD binding (GO:0050660)
10 (351)1 (2331)2 (1318)IPR013547: Prolyl 4-hydroxylase alpha-subunit, N-terminal
10 (352)4 (641)3 (926)IPR013649: Integrin alpha-2
10 (353)11 (200)11 (257)IPR013655: PAS fold-3
10 (354)7 (350)5 (585)IPR013740: RedoxinMolecular Function: oxidoreductase activity (GO:0016491)
10 (355)11 (201)10 (280)IPR013767: PAS foldBiological Process: regulation of transcription, DNA-dependent (GO:0006355)
9 (356)2 (875)4 (589)IPR000072: Platelet-derived growth factor (PDGF)Molecular Function: growth factor activity (GO:0008083), Cellular Component: membrane (GO:0016020)
9 (357)7 (298)7 (366)IPR000095: PAK-box/P21-Rho-binding
9 (358)5 (415)4 (595)IPR000203: GPSBiological Process: neuropeptide signaling pathway (GO:0007218), Cellular Component: membrane (GO:0016020)
9 (359)6 (356)7 (369)IPR000425: Major intrinsic proteinMolecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
9 (360)4 (515)10 (260)IPR000602: Glycoside hydrolase, family 38Molecular Function: alpha-mannosidase activity (GO:0004559), Biological Process: carbohydrate metabolic process (GO:0005975)
9 (361)7 (305)8 (325)IPR000651: Guanine nucleotide exchange factor for Ras-like GTPases, N-terminalMolecular Function: guanyl-nucleotide exchange factor activity (GO:0005085), Cellular Component: intracellular (GO:0005622), Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056)
9 (362)5 (426)7 (372)IPR000857: Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4Cellular Component: cytoskeleton (GO:0005856)
9 (363)10 (208)8 (326)IPR000861: PKN/rhophilin/rhotekin rho-binding repeatCellular Component: intracellular (GO:0005622), Biological Process: signal transduction (GO:0007165)
9 (364)4 (527)6 (441)IPR001194: DENN
9 (365)12 (168)13 (207)IPR001199: Cytochrome b5Molecular Function: heme binding (GO:0020037), Molecular Function: transition metal ion binding (GO:0046914)
9 (366)7 (312)8 (331)IPR001298: Filamin/ABP280 repeat
9 (367)9 (236)14 (191)IPR001327: Pyridine nucleotide-disulphide oxidoreductase, NAD-binding regionBiological Process: electron transport (GO:0006118), Molecular Function: disulfide oxidoreductase activity (GO:0015036)
9 (368)7 (314)7 (379)IPR001374: Single-stranded nucleic acid binding R3HMolecular Function: nucleic acid binding (GO:0003676)
9 (369)4 (540)6 (446)IPR001548: Peptidase M2, peptidyl-dipeptidase AMolecular Function: peptidyl-dipeptidase A activity (GO:0004246), Biological Process: proteolysis (GO:0006508), Cellular Component: membrane (GO:0016020)
9 (370)10 (216)11 (240)IPR002068: Heat shock protein Hsp20
9 (371)10 (218)16 (165)IPR002159: CD36 antigenBiological Process: cell adhesion (GO:0007155), Cellular Component: membrane (GO:0016020)
9 (372)5 (454)8 (345)IPR003172: E1 protein and Def2/Der2 allergen
9 (373)7 (330)6 (463)IPR003323: Ovarian tumour, otubain
9 (374)11 (191)11 (247)IPR004012: RUN
9 (375)6 (390)5 (544)IPR004367: Cyclin, C-terminalBiological Process: regulation of progression through cell cycle (GO:0000074), Cellular Component: nucleus (GO:0005634)
9 (376)5 (462)6 (471)IPR005112: dDENN
9 (377)5 (466)2 (1133)IPR005331: Carbohydrate sulphotransferase
9 (378)5 (467)5 (547)IPR005514: Protein of unknown function DUF316
9 (379)7 (340)5 (549)IPR005814: Aminotransferase class-IIIMolecular Function: transaminase activity (GO:0008483), Molecular Function: pyridoxal phosphate binding (GO:0030170)
9 (380)6 (393)7 (412)IPR006068: ATPase, P-type cation-transporter, C-terminalBiological Process: cation transport (GO:0006812), Molecular Function: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism (GO:0015662), Cellular Component: membrane (GO:0016020)
9 (381)7 (341)13 (216)IPR006569: Regulation of nuclear pre-mRNA protein
9 (382)9 (257)9 (310)IPR006575: RWD
9 (383)1 (1818)1 (1886)IPR007075: RNA polymerase Rpb1, domain 6Molecular Function: DNA binding (GO:0003677), Molecular Function: DNA-directed RNA polymerase activity (GO:0003899), Biological Process: transcription (GO:0006350)
9 (384)5 (483)5 (564)IPR007484: Peptidase M28Biological Process: proteolysis (GO:0006508), Molecular Function: peptidase activity (GO:0008233)
9 (385)2 (1144)3 (880)IPR007848: Methyltransferase smallMolecular Function: methyltransferase activity (GO:0008168)
9 (386)3 (836)4 (709)IPR009040: Ferritin-like
9 (387)6 (406)7 (423)IPR010900: Nicotine adenine dinucleotide glycohydrolase
9 (388)2 (1215)3 (915)IPR012948: AARP2CN
9 (389)6 (408)5 (580)IPR013093: ATPase AAA-2
9 (390)4 (640)4 (727)IPR013618: Domain of unknown function DUF1736
9 (391)9 (264)10 (281)IPR014045: Protein phosphatase 2C-like
8 (392)4 (506)9 (282)IPR000322: Glycoside hydrolase, family 31Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553), Biological Process: carbohydrate metabolic process (GO:0005975)
8 (393)4 (507)4 (596)IPR000323: Copper type II, ascorbate-dependent monooxygenase, coreMolecular Function: monooxygenase activity (GO:0004497), Molecular Function: copper ion binding (GO:0005507)
8 (394)6 (354)7 (367)IPR000331: Rap/ran-GAPMolecular Function: GTPase activator activity (GO:0005096), Cellular Component: intracellular (GO:0005622), Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056)
8 (395)14 (140)16 (159)IPR000560: Histidine acid phosphataseMolecular Function: acid phosphatase activity (GO:0003993)
8 (396)9 (231)9 (285)IPR000731: Sterol-sensing 5TM box
8 (397)5 (425)6 (437)IPR000836: PhosphoribosyltransferaseBiological Process: nucleoside metabolic process (GO:0009116)
8 (398)8 (270)7 (373)IPR000938: CAP-Gly
8 (399)4 (522)9 (288)IPR000990: InnexinCellular Component: gap junction (GO:0005921)
8 (400)7 (309)6 (440)IPR001025: Bromo adjacent regionMolecular Function: DNA binding (GO:0003677)
8 (401)5 (435)4 (625)IPR001564: Nucleoside diphosphate kinaseMolecular Function: nucleoside diphosphate kinase activity (GO:0004550), Molecular Function: ATP binding (GO:0005524), Biological Process: GTP biosynthetic process (GO:0006183), Biological Process: UTP biosynthetic process (GO:0006228), Biological Process: CTP biosynthetic process (GO:0006241)
8 (402)9 (239)9 (292)IPR001606: AT-rich interaction regionMolecular Function: DNA binding (GO:0003677), Cellular Component: intracellular (GO:0005622)
8 (403)10 (211)5 (510)IPR001607: Zinc finger, UBP-typeMolecular Function: zinc ion binding (GO:0008270)
8 (404)7 (321)5 (514)IPR001737: Ribosomal RNA adenine methylase transferaseBiological Process: rRNA modification (GO:0000154), Molecular Function: rRNA (adenine-N6,N6-)-dimethyltransferase activity (GO:0000179), Molecular Function: rRNA methyltransferase activity (GO:0008649)
8 (405)6 (379)5 (523)IPR002877: Ribosomal RNA methyltransferase RrmJ/FtsJ
8 (406)9 (245)11 (242)IPR002909: Cell surface receptor IPT/TIG
8 (407)5 (450)4 (654)IPR002942: RNA-binding S4Molecular Function: RNA binding (GO:0003723)
8 (408)7 (328)13 (212)IPR003034: DNA-binding SAPMolecular Function: nucleic acid binding (GO:0003676)
8 (409)9 (247)11 (243)IPR003104: Actin-binding FH2Molecular Function: actin binding (GO:0003779), Biological Process: cellular component organization and biogenesis (GO:0016043), Biological Process: actin cytoskeleton organization and biogenesis (GO:0030036)
8 (410)7 (329)7 (397)IPR003107: RNA-processing protein, HAT helixCellular Component: intracellular (GO:0005622), Biological Process: RNA processing (GO:0006396)
8 (411)5 (455)5 (532)IPR003307: eIF4-gamma/eIF5/eIF2-epsilonMolecular Function: translation initiation factor activity (GO:0003743), Biological Process: regulation of translational initiation (GO:0006446)
8 (412)1 (1555)1 (1624)IPR003644: Na-Ca exchanger/integrin-beta4Biological Process: cell communication (GO:0007154), Cellular Component: integral to membrane (GO:0016021)
8 (413)4 (577)5 (537)IPR003891: Initiation factor eIF-4 gamma, MA3
8 (414)3 (741)5 (539)IPR004019: YLP motif
8 (415)3 (742)3 (814)IPR004022: DDT
8 (416)7 (335)7 (410)IPR004182: GRAM
8 (417)9 (253)6 (467)IPR004274: NLI interacting factor
8 (418)7 (338)6 (468)IPR004837: Sodium/calcium exchanger membrane regionCellular Component: integral to membrane (GO:0016021)
8 (419)8 (286)9 (305)IPR004853: Protein of unknown function DUF250
8 (420)2 (1080)1 (1790)IPR006050: DNA photolyase, N-terminalMolecular Function: DNA photolyase activity (GO:0003913), Biological Process: DNA repair (GO:0006281)
8 (421)3 (775)5 (551)IPR006085: XPG N-terminalMolecular Function: nuclease activity (GO:0004518), Biological Process: DNA repair (GO:0006281)
8 (422)4 (609)9 (311)IPR006634: TRAM, LAG1 and CLN8 homologyCellular Component: integral to membrane (GO:0016021)
8 (423)7 (343)6 (477)IPR006644: Dystroglycan-type cadherin-likeMolecular Function: calcium ion binding (GO:0005509), Molecular Function: protein binding (GO:0005515)
8 (424)1 (1766)1 (1838)IPR006818: Anti-silencing protein, ASF1-like
8 (425)1 (1780)2 (1181)IPR006906: Timeless protein
8 (426)2 (1121)2 (1186)IPR007034: Protein of unknown function DUF663
8 (427)5 (481)5 (560)IPR007109: Brix
8 (428)6 (397)7 (417)IPR007123: Gelsolin region
8 (429)6 (398)8 (353)IPR007197: Radical SAMMolecular Function: catalytic activity (GO:0003824), Molecular Function: iron ion binding (GO:0005506)
8 (430)2 (1125)2 (1199)IPR007271: Nucleotide-sugar transporterCellular Component: Golgi membrane (GO:0000139), Molecular Function: sugar porter activity (GO:0005351), Biological Process: carbohydrate transport (GO:0008643), Cellular Component: integral to membrane (GO:0016021)
8 (431)7 (344)9 (313)IPR007696: MutS IIIBiological Process: DNA metabolic process (GO:0006259)
8 (432)3 (823)3 (877)IPR007757: MT-A70Cellular Component: nucleus (GO:0005634), Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (GO:0006139), Molecular Function: methyltransferase activity (GO:0008168)
8 (433)12 (174)8 (357)IPR008197: Whey acidic protein, core region
8 (434)10 (225)10 (275)IPR008671: Lycopene beta and epsilon cyclaseBiological Process: carotenoid biosynthetic process (GO:0016117), Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
8 (435)1 (2216)2 (1276)IPR011442: Protein of unknown function DUF1546Molecular Function: RNA polymerase II transcription factor activity (GO:0003702), Cellular Component: nucleus (GO:0005634), Molecular Function: transcription initiation factor activity (GO:0016986), Biological Process: regulation of transcription factor activity (GO:0051090)
8 (436)7 (347)6 (485)IPR011611: PfkB
8 (437)6 (410)4 (724)IPR013144: CT11-RanBPM
8 (438)1 (2369)1 (2395)IPR013846: mRNA capping enzyme, C-terminal
7 (439)7 (300)32 (70)IPR000215: Proteinase inhibitor I4, serpinMolecular Function: serine-type endopeptidase inhibitor activity (GO:0004867)
7 (440)4 (509)5 (490)IPR000432: DNA mismatch repair protein MutS, C-terminalMolecular Function: damaged DNA binding (GO:0003684), Molecular Function: ATP binding (GO:0005524), Biological Process: mismatch repair (GO:0006298)
7 (441)7 (306)5 (496)IPR000760: Inositol monophosphataseMolecular Function: inositol or phosphatidylinositol phosphatase activity (GO:0004437)
7 (442)7 (308)10 (263)IPR000877: Proteinase inhibitor I12, Bowman-BirkMolecular Function: serine-type endopeptidase inhibitor activity (GO:0004867), Cellular Component: extracellular region (GO:0005576)
7 (443)2 (901)3 (751)IPR000889: Glutathione peroxidaseMolecular Function: glutathione peroxidase activity (GO:0004602), Biological Process: response to oxidative stress (GO:0006979)
7 (444)8 (269)14 (189)IPR000917: SulfataseBiological Process: metabolic process (GO:0008152), Molecular Function: sulfuric ester hydrolase activity (GO:0008484)
7 (445)3 (664)4 (611)IPR000967: Zinc finger, NF-X1-typeMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355), Molecular Function: zinc ion binding (GO:0008270)
7 (446)9 (234)9 (290)IPR001206: Diacylglycerol kinase, catalytic regionMolecular Function: diacylglycerol kinase activity (GO:0004143), Biological Process: protein kinase C activation (GO:0007205)
7 (447)4 (528)4 (616)IPR001263: Phosphoinositide 3-kinase accessory region PIKMolecular Function: inositol or phosphatidylinositol kinase activity (GO:0004428)
7 (448)5 (432)4 (620)IPR001370: Proteinase inhibitor I32, inhibitor of apoptosisCellular Component: intracellular (GO:0005622), Biological Process: anti-apoptosis (GO:0006916)
7 (449)4 (534)4 (621)IPR001382: Glycoside hydrolase, family 47Molecular Function: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (GO:0004571), Molecular Function: calcium ion binding (GO:0005509), Cellular Component: membrane (GO:0016020)
7 (450)4 (539)8 (337)IPR001526: CD59 antigen
7 (451)6 (368)8 (339)IPR001627: Semaphorin/CD100 antigen
7 (452)7 (320)8 (340)IPR001699: Transcription factor, T-boxMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
7 (453)4 (543)4 (629)IPR001736: Phospholipase D/TransphosphatidylaseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolic process (GO:0008152)
7 (454)3 (697)6 (453)IPR002138: Peptidase C14, caspase non-catalytic subunit p10Biological Process: proteolysis (GO:0006508), Molecular Function: caspase activity (GO:0030693)
7 (455)5 (441)6 (454)IPR002218: Glucose-inhibited division protein ABiological Process: tRNA processing (GO:0008033), Molecular Function: FAD binding (GO:0050660)
7 (456)7 (325)6 (457)IPR002524: Cation efflux proteinBiological Process: cation transport (GO:0006812), Molecular Function: cation transporter activity (GO:0008324), Cellular Component: membrane (GO:0016020)
7 (457)4 (563)4 (648)IPR002884: Proprotein convertase, PMolecular Function: subtilase activity (GO:0004289), Biological Process: proteolysis (GO:0006508)
7 (458)1 (1509)1 (1578)IPR003002: 7TM chemoreceptor, subfamily 1
7 (459)6 (382)7 (395)IPR003018: GAF
7 (460)4 (569)4 (661)IPR003137: Protease-associated PABiological Process: proteolysis (GO:0006508), Molecular Function: peptidase activity (GO:0008233)
7 (461)6 (388)6 (465)IPR004038: Ribosomal protein L7Ae/L30e/S12e/Gadd45
7 (462)6 (392)9 (306)IPR005024: Snf7Biological Process: protein transport (GO:0015031)
7 (463)1 (1846)2 (1191)IPR007199: Replication factor-A protein 1, N-terminalMolecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: DNA replication (GO:0006260)
7 (464)8 (291)7 (418)IPR007863: Peptidase M16, C-terminal
7 (465)1 (2014)1 (2062)IPR008501: Protein of unknown function DUF783
7 (466)2 (1193)4 (718)IPR011625: Alpha-2-macroglobulin, N-terminal 2
7 (467)9 (263)9 (316)IPR011761: ATP-grasp foldMolecular Function: catalytic activity (GO:0003824), Molecular Function: ATP binding (GO:0005524)
7 (468)5 (493)6 (486)IPR011765: Peptidase M16, N-terminal
7 (469)6 (407)6 (487)IPR013078: Phosphoglycerate mutase
7 (470)6 (412)4 (725)IPR013517: FG-GAP
7 (471)4 (639)5 (583)IPR013598: Exportin-1/Importin-beta-like
7 (472)3 (871)4 (730)IPR014743: Chloride channel, core
6 (473)9 (227)4 (590)IPR000092: Polyprenyl synthetaseBiological Process: isoprenoid biosynthetic process (GO:0008299)
6 (474)2 (878)3 (733)IPR000197: Zinc finger, TAZ-typeMolecular Function: transcription cofactor activity (GO:0003712), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355), Molecular Function: zinc ion binding (GO:0008270)
6 (475)3 (646)3 (736)IPR000270: Octicosapeptide/Phox/Bem1p
6 (476)5 (418)4 (597)IPR000409: Beige/BEACH
6 (477)1 (1288)256 (4)IPR000477: RNA-directed DNA polymerase (Reverse transcriptase)Molecular Function: RNA binding (GO:0003723), Molecular Function: RNA-directed DNA polymerase activity (GO:0003964), Biological Process: RNA-dependent DNA replication (GO:0006278)
6 (478)3 (648)4 (599)IPR000494: EGF receptor, L domainMolecular Function: transmembrane receptor protein tyrosine kinase activity (GO:0004714), Molecular Function: epidermal growth factor receptor activity (GO:0005006), Cellular Component: membrane (GO:0016020)
6 (479)1 (1296)2 (948)IPR000559: Formate-tetrahydrofolate ligase, FTHFSMolecular Function: formate-tetrahydrofolate ligase activity (GO:0004329), Molecular Function: ATP binding (GO:0005524), Biological Process: folic acid and derivative biosynthetic process (GO:0009396)
6 (480)7 (301)9 (284)IPR000601: PKD
6 (481)7 (303)6 (436)IPR000640: Translation elongation factor EFG/EF2, C-terminalMolecular Function: GTP binding (GO:0005525)
6 (482)5 (424)4 (610)IPR000804: Clathrin adaptor complex, small chainBiological Process: intracellular protein transport (GO:0006886), Cellular Component: coated vesicle membrane (GO:0030662)
6 (483)3 (661)2 (961)IPR000835: Bacterial regulatory protein, MarRMolecular Function: transcription factor activity (GO:0003700), Cellular Component: intracellular (GO:0005622), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
6 (484)8 (268)10 (262)IPR000867: Insulin-like growth factor-binding protein, IGFBPBiological Process: regulation of cell growth (GO:0001558), Molecular Function: insulin-like growth factor binding (GO:0005520), Cellular Component: extracellular region (GO:0005576)
6 (485)2 (907)2 (969)IPR000959: POLO box duplicated regionMolecular Function: protein binding (GO:0005515)
6 (486)3 (665)4 (612)IPR000981: Neurohypophysial hormoneMolecular Function: neurohypophyseal hormone activity (GO:0005185), Cellular Component: extracellular region (GO:0005576)
6 (487)4 (525)3 (754)IPR001078: Catalytic domain of components of various dehydrogenase complexesBiological Process: metabolic process (GO:0008152), Molecular Function: acyltransferase activity (GO:0008415)
6 (488)2 (914)3 (755)IPR001079: Galectin, galactose-binding lectinMolecular Function: sugar binding (GO:0005529)
6 (489)1 (1348)2 (982)IPR001135: NADH-ubiquinone oxidoreductase, chain 49kDaBiological Process: electron transport (GO:0006118), Molecular Function: electron carrier activity (GO:0009055), Molecular Function: oxidoreductase activity, acting on NADH or NADPH (GO:0016651), Molecular Function: NAD binding (GO:0051287)
6 (490)6 (363)5 (504)IPR001190: Speract/scavenger receptorMolecular Function: scavenger receptor activity (GO:0005044), Cellular Component: membrane (GO:0016020)
6 (491)4 (531)8 (332)IPR001300: Peptidase C2, calpainMolecular Function: calpain activity (GO:0004198), Cellular Component: intracellular (GO:0005622), Biological Process: proteolysis (GO:0006508)
6 (492)4 (533)2 (993)IPR001368: TNFR/CD27/30/40/95 cysteine-rich regionMolecular Function: receptor activity (GO:0004872)
6 (493)7 (317)6 (445)IPR001451: Bacterial transferase hexapeptide repeatMolecular Function: acyltransferase activity (GO:0008415)
6 (494)8 (276)15 (177)IPR001529: DNA-directed RNA polymerase, M/15 kDa subunitMolecular Function: DNA binding (GO:0003677), Molecular Function: DNA-directed RNA polymerase activity (GO:0003899), Biological Process: transcription (GO:0006350)
6 (495)1 (1382)1 (1446)IPR001568: Ribonuclease T2Molecular Function: RNA binding (GO:0003723), Molecular Function: endoribonuclease activity (GO:0004521)
6 (496)2 (954)3 (777)IPR001898: Sodium/sulphate symporterMolecular Function: transporter activity (GO:0005215), Biological Process: sodium ion transport (GO:0006814), Cellular Component: membrane (GO:0016020)
6 (497)4 (549)7 (385)IPR001952: Alkaline phosphataseBiological Process: metabolic process (GO:0008152)
6 (498)3 (695)2 (1017)IPR002087: Anti-proliferative protein
6 (499)5 (437)9 (296)IPR002109: GlutaredoxinMolecular Function: electron carrier activity (GO:0009055), Molecular Function: protein disulfide oxidoreductase activity (GO:0015035), Biological Process: cell redox homeostasis (GO:0045454)
6 (500)2 (974)4 (644)IPR002529: Fumarylacetoacetate (FAA) hydrolaseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolic process (GO:0008152)