Top 500 InterPro hits

statistically significant differences are marked in bold (p-value of chi-square test < 0.01 without correction for multiple tests).
Apis mellifera (honey bee)
10157 total genes
( 71% w domains)
Drosophila melanogaster (fruit fly)
13450 total genes
( 68% w domains)
Homo sapiens (man)
22218 total genes
( 72% w domains)
FamilyGO terms
227531715083Transmembrane
108128954083Signal peptide
247 (1)314 (1)778 (1)IPR007087: Zinc finger, C2H2-typeMolecular Function: nucleic acid binding (GO:0003676), Cellular Component: nucleus (GO:0005634), Molecular Function: zinc ion binding (GO:0008270)
201 (2)207 (3)464 (3)IPR000719: Protein kinaseMolecular Function: protein kinase activity (GO:0004672), Molecular Function: ATP binding (GO:0005524), Biological Process: protein amino acid phosphorylation (GO:0006468)
184 (3)184 (4)261 (9)IPR001680: WD-40 repeat
120 (4)121 (8)462 (4)IPR003599: Immunoglobulin subtype
117 (5)119 (9)285 (7)IPR001841: Zinc finger, RING-typeCellular Component: ubiquitin ligase complex (GO:0000151), Molecular Function: ubiquitin-protein ligase activity (GO:0004842), Molecular Function: zinc ion binding (GO:0008270), Biological Process: protein ubiquitination (GO:0016567)
116 (6)122 (7)133 (28)IPR003593: AAA ATPaseMolecular Function: nucleotide binding (GO:0000166), Molecular Function: nucleoside-triphosphatase activity (GO:0017111)
114 (7)128 (6)236 (12)IPR000504: RNA-binding region RNP-1 (RNA recognition motif)Molecular Function: nucleic acid binding (GO:0003676)
107 (8)107 (10)221 (15)IPR001611: Leucine-rich repeat
100 (9)103 (11)244 (11)IPR002290: Serine/threonine protein kinaseMolecular Function: protein serine/threonine kinase activity (GO:0004674), Molecular Function: ATP binding (GO:0005524), Biological Process: protein amino acid phosphorylation (GO:0006468)
98 (10)130 (5)99 (38)IPR011701: Major facilitator superfamily MFS_1
97 (11)82 (20)247 (10)IPR002110: Ankyrin
97 (12)102 (12)369 (5)IPR007110: Immunoglobulin-like
96 (13)100 (14)220 (16)IPR003598: Immunoglobulin C2 type
89 (14)99 (15)226 (14)IPR001356: HomeoboxMolecular Function: DNA binding (GO:0003677), Molecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
83 (15)61 (33) ()IPR004117: Olfactory receptor, DrosophilaMolecular Function: olfactory receptor activity (GO:0004984), Molecular Function: odorant binding (GO:0005549), Biological Process: perception of smell (GO:0007608), Cellular Component: membrane (GO:0016020)
78 (16)67 (30)265 (8)IPR001849: Pleckstrin-like
78 (17)74 (25)109 (34)IPR011545: DEAD/DEAH box helicase, N-terminalMolecular Function: nucleic acid binding (GO:0003676), Molecular Function: helicase activity (GO:0004386), Molecular Function: ATP binding (GO:0005524)
75 (18)76 (22)140 (26)IPR001440: TPR repeat
74 (19)76 (23)107 (35)IPR001650: Helicase, C-terminalMolecular Function: nucleic acid binding (GO:0003676), Molecular Function: helicase activity (GO:0004386), Molecular Function: ATP binding (GO:0005524)
73 (20)71 (28)208 (17)IPR001452: SH3
72 (21)76 (24)160 (23)IPR003591: Leucine-rich repeat, typical subtype
71 (22)68 (29)166 (22)IPR000210: BTB/POZMolecular Function: protein binding (GO:0005515)
69 (23)84 (19)183 (19)IPR002048: Calcium-binding EF-handMolecular Function: calcium ion binding (GO:0005509)
69 (24)89 (16)232 (13)IPR003656: Zinc finger, BED-type predictedMolecular Function: DNA binding (GO:0003677)
67 (25)56 (36)102 (37)IPR000357: HEAT
66 (26)63 (31)143 (25)IPR001478: PDZ/DHR/GLGFMolecular Function: protein binding (GO:0005515)
63 (27)56 (39)180 (20)IPR011511: Variant SH3
58 (28)243 (2)120 (30)IPR001254: Peptidase S1 and S6, chymotrypsin/HapMolecular Function: trypsin activity (GO:0004295), Biological Process: proteolysis and peptidolysis (GO:0006508)
58 (29)61 (32)179 (21)IPR003961: Fibronectin, type III
57 (30)61 (34)191 (18)IPR006210: Type I EGF
55 (31)71 (27)704 (2)IPR000276: Rhodopsin-like GPCR superfamilyMolecular Function: rhodopsin-like receptor activity (GO:0001584), Biological Process: G-protein coupled receptor protein signaling pathway (GO:0007186), Cellular Component: integral to membrane (GO:0016021)
53 (32)58 (35)112 (31)IPR001092: Basic helix-loop-helix dimerisation region bHLHCellular Component: nucleus (GO:0005634), Molecular Function: transcription regulator activity (GO:0030528), Biological Process: regulation of transcription (GO:0045449)
53 (33)72 (26)38 (116)IPR005828: General substrate transporterMolecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: integral to membrane (GO:0016021)
51 (34)55 (40)130 (29)IPR001806: Ras GTPaseMolecular Function: GTP binding (GO:0005525), Biological Process: small GTPase mediated signal transduction (GO:0007264)
48 (35)40 (47)134 (27)IPR000008: C2
47 (36)86 (18)61 (64)IPR001128: Cytochrome P450Molecular Function: monooxygenase activity (GO:0004497), Molecular Function: iron ion binding (GO:0005506), Biological Process: electron transport (GO:0006118), Molecular Function: heme binding (GO:0020037)
44 (37)40 (50)150 (24)IPR006209: EGF-like
43 (38)56 (37)57 (68)IPR002198: Short-chain dehydrogenase/reductase SDRBiological Process: metabolism (GO:0008152), Molecular Function: oxidoreductase activity (GO:0016491)
40 (39)42 (45)81 (48)IPR001965: Zinc finger, PHD-typeMolecular Function: protein binding (GO:0005515), Biological Process: regulation of transcription, DNA-dependent (GO:0006355), Molecular Function: zinc ion binding (GO:0008270)
39 (40)56 (38)49 (83)IPR003439: ABC transporter relatedMolecular Function: ATP binding (GO:0005524), Molecular Function: ATPase activity (GO:0016887)
39 (41)41 (46)44 (102)IPR003959: AAA ATPase, central regionMolecular Function: ATP binding (GO:0005524)
38 (42)81 (21)2 (1621)IPR002557: Chitin binding Peritrophin-ACellular Component: extracellular region (GO:0005576), Biological Process: chitin metabolism (GO:0006030), Molecular Function: chitin binding (GO:0008061)
33 (43)43 (44)44 (101)IPR002172: Low density lipoprotein-receptor, class A
33 (44)38 (52)111 (32)IPR005821: Ion transport proteinMolecular Function: ion channel activity (GO:0005216), Biological Process: ion transport (GO:0006811), Cellular Component: membrane (GO:0016020)
32 (45)46 (43)54 (71)IPR001993: Mitochondrial substrate carrierMolecular Function: binding (GO:0005488), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
31 (46)100 (13) ()IPR000618: Insect cuticle proteinMolecular Function: structural constituent of cuticle (GO:0042302)
31 (47)32 (62)109 (33)IPR000980: SH2 motifBiological Process: intracellular signaling cascade (GO:0007242)
31 (48)34 (59)69 (54)IPR001781: LIM, zinc-bindingMolecular Function: zinc ion binding (GO:0008270)
30 (49)30 (67)92 (39)IPR001245: Tyrosine protein kinaseMolecular Function: protein-tyrosine kinase activity (GO:0004713), Molecular Function: ATP binding (GO:0005524), Biological Process: protein amino acid phosphorylation (GO:0006468)
29 (50)32 (63)103 (36)IPR001881: EGF-like calcium-bindingMolecular Function: calcium ion binding (GO:0005509)
28 (51)31 (66)86 (42)IPR000048: IQ calmodulin-binding region
28 (52)27 (78)44 (98)IPR001214: Nuclear protein SET
28 (53)36 (53)60 (66)IPR001810: Cyclin-like F-box
27 (54)32 (60)46 (90)IPR000608: Ubiquitin-conjugating enzyme, E2Biological Process: protein modification (GO:0006464), Biological Process: ubiquitin cycle (GO:0006512), Molecular Function: ubiquitin-like activating enzyme activity (GO:0008642)
27 (55)40 (49)49 (81)IPR001623: Heat shock protein DnaJ, N-terminalBiological Process: protein folding (GO:0006457), Molecular Function: heat shock protein binding (GO:0031072), Molecular Function: unfolded protein binding (GO:0051082)
27 (56)35 (56)15 (317)IPR002018: Carboxylesterase, type B
26 (57)24 (93)50 (77)IPR000571: Zinc finger, CCCH-typeMolecular Function: nucleic acid binding (GO:0003676)
26 (58)29 (71)78 (51)IPR001660: Sterile alpha motif SAM
26 (59)26 (84)45 (93)IPR001752: Kinesin, motor regionMolecular Function: microtubule motor activity (GO:0003777), Molecular Function: ATP binding (GO:0005524), Cellular Component: microtubule associated complex (GO:0005875), Biological Process: microtubule-based movement (GO:0007018)
26 (60)26 (85)62 (62)IPR002219: Protein kinase C, phorbol ester/diacylglycerol bindingBiological Process: intracellular signaling cascade (GO:0007242)
26 (61)89 (17)1 (3049)IPR012934: Zinc finger, AD-type
25 (62)20 (123)57 (67)IPR000219: DH
25 (63)25 (88)83 (46)IPR000483: Cysteine-rich flanking region, C-terminal
25 (64)27 (79)65 (59)IPR001715: Calponin-like actin-binding
24 (65)24 (97)48 (87)IPR001005: Myb, DNA-bindingMolecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634)
24 (66)24 (98)44 (100)IPR001878: Zinc finger, CCHC-typeMolecular Function: nucleic acid binding (GO:0003676)
24 (67)13 (218) ()IPR003534: Major royal jelly protein
23 (68)20 (122)68 (55)IPR000198: RhoGAP
23 (69)24 (94)53 (73)IPR000626: UbiquitinBiological Process: protein modification (GO:0006464)
23 (70)22 (103)62 (61)IPR000910: HMG1/2 (high mobility group) boxMolecular Function: DNA binding (GO:0003677), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
23 (71)25 (89)53 (74)IPR000961: Protein kinase, C-terminalMolecular Function: protein serine/threonine kinase activity (GO:0004674), Molecular Function: ATP binding (GO:0005524), Biological Process: protein amino acid phosphorylation (GO:0006468)
23 (72)18 (138)45 (94)IPR001791: Laminin G
23 (73)29 (72)36 (126)IPR004087: KHMolecular Function: nucleic acid binding (GO:0003676)
22 (74)21 (115)48 (85)IPR000299: Band 4.1Cellular Component: cytoskeleton (GO:0005856)
22 (75)23 (100)44 (97)IPR001202: WW/Rsp5/WWP
22 (76)22 (106)54 (70)IPR001394: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2Molecular Function: cysteine-type endopeptidase activity (GO:0004197), Molecular Function: ubiquitin thiolesterase activity (GO:0004221), Biological Process: ubiquitin-dependent protein catabolism (GO:0006511)
22 (77)30 (69)61 (65)IPR003579: Ras small GTPase, Rab typeMolecular Function: GTP binding (GO:0005525), Biological Process: small GTPase mediated signal transduction (GO:0007264), Biological Process: protein transport (GO:0015031)
22 (78)22 (111)72 (53)IPR011510: Sterile alpha motif homology 2
21 (79)21 (114)47 (88)IPR000195: RabGAP/TBC
21 (80)17 (144)48 (84)IPR000225: Armadillo
21 (81)16 (163)65 (58)IPR000884: Thrombospondin, type I
21 (82)21 (118)47 (89)IPR001628: Nuclear hormone receptor, DNA-bindingMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
21 (83)26 (86)49 (82)IPR002867: Zinc finger, C6HC-type
21 (84)28 (76)35 (129)IPR004088: KH, type 1Molecular Function: nucleic acid binding (GO:0003676)
21 (85)21 (120)44 (103)IPR006029: Neurotransmitter-gated ion-channel transmembrane regionBiological Process: ion transport (GO:0006811), Cellular Component: membrane (GO:0016020), Molecular Function: neurotransmitter receptor activity (GO:0030594)
21 (86)21 (121)46 (91)IPR006202: Neurotransmitter-gated ion-channel ligand-bindingMolecular Function: extracellular ligand-gated ion channel activity (GO:0005230), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
20 (87)15 (178)1 (2023)IPR000172: Glucose-methanol-choline oxidoreductaseBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
20 (88)30 (68)22 (210)IPR001251: Cellular retinaldehyde-binding/triple function, C-terminal
20 (89)20 (127)50 (78)IPR004827: Basic-leucine zipper (bZIP) transcription factorMolecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
20 (90)12 (241)89 (40)IPR007125: Histone coreMolecular Function: DNA binding (GO:0003677)
20 (91)15 (196)1 (2664)IPR007867: GMC oxidoreductaseMolecular Function: oxidoreductase activity, acting on CH-OH group of donors (GO:0016614), Molecular Function: FAD binding (GO:0050660)
20 (92)17 (156)37 (122)IPR012680: Laminin G, subdomain 2
19 (93)26 (81)34 (131)IPR000449: Ubiquitin-associated
19 (94)18 (133)34 (133)IPR000595: Cyclic nucleotide-binding
19 (95)28 (75)17 (284)IPR001509: NAD-dependent epimerase/dehydrataseMolecular Function: catalytic activity (GO:0003824), Biological Process: nucleotide-sugar metabolism (GO:0009225), Molecular Function: NAD binding (GO:0051287)
19 (96)12 (229)38 (115)IPR001609: Myosin head, motor regionMolecular Function: motor activity (GO:0003774), Molecular Function: ATP binding (GO:0005524), Cellular Component: myosin (GO:0016459)
19 (97)15 (186)44 (99)IPR001683: Phox-likeBiological Process: intracellular signaling cascade (GO:0007242)
19 (98)23 (101)37 (118)IPR001828: Extracellular ligand-binding receptor
19 (99)32 (65)27 (171)IPR004843: MetallophosphoesteraseMolecular Function: hydrolase activity (GO:0016787)
19 (100)17 (152)68 (56)IPR006652: Kelch repeat
19 (101)17 (153)40 (112)IPR006670: Cyclin
18 (102)34 (58)32 (141)IPR000301: CD9/CD37/CD63 antigenCellular Component: integral to membrane (GO:0016021)
18 (103)16 (161)49 (80)IPR000536: Nuclear hormone receptor, ligand-bindingMolecular Function: transcription factor activity (GO:0003700), Molecular Function: steroid hormone receptor activity (GO:0003707), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
18 (104)24 (96)48 (86)IPR000859: CUB
18 (105)25 (90)20 (236)IPR001054: Adenylyl cyclase class-3/4/guanylyl cyclaseBiological Process: intracellular signaling cascade (GO:0007242), Biological Process: cyclic nucleotide biosynthesis (GO:0009190), Molecular Function: phosphorus-oxygen lyase activity (GO:0016849)
18 (106)18 (135)21 (226)IPR001163: Like-Sm ribonucleoprotein, coreCellular Component: nucleus (GO:0005634), Cellular Component: small nucleolar ribonucleoprotein complex (GO:0005732), Biological Process: mRNA processing (GO:0006397)
18 (107)18 (136)40 (109)IPR001487: Bromodomain
18 (108)26 (87)38 (117)IPR005834: Haloacid dehalogenase-like hydrolaseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolism (GO:0008152)
18 (109)16 (175)68 (57)IPR011498: Kelch
18 (110)18 (143)40 (114)IPR011700: Basic leucine zipperMolecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
17 (111)21 (113)19 (247)IPR000182: GCN5-related N-acetyltransferaseMolecular Function: N-acetyltransferase activity (GO:0008080)
17 (112)17 (148)80 (50)IPR002126: CadherinMolecular Function: calcium ion binding (GO:0005509), Biological Process: homophilic cell adhesion (GO:0007156), Cellular Component: membrane (GO:0016020)
17 (113)16 (170)20 (241)IPR002893: Zinc finger, MYND-type
17 (114)17 (149)21 (228)IPR002917: GTP-binding protein, HSR1-related
17 (115)19 (131)22 (218)IPR006662: Thioredoxin-relatedMolecular Function: electron transporter activity (GO:0005489), Biological Process: electron transport (GO:0006118)
17 (116)16 (177)31 (151)IPR012679: Laminin G, subdomain 1
16 (117)15 (179)25 (177)IPR000253: Forkhead-associated
16 (118)12 (225)27 (169)IPR000306: Zinc finger, FYVE-typeMolecular Function: zinc ion binding (GO:0008270)
16 (119)17 (145)31 (146)IPR000330: SNF2-relatedMolecular Function: DNA binding (GO:0003677), Molecular Function: ATP binding (GO:0005524)
16 (120)15 (180)86 (43)IPR000372: Cysteine-rich flanking region, N-terminal
16 (121)16 (160)20 (233)IPR000467: D111/G-patchMolecular Function: nucleic acid binding (GO:0003676), Cellular Component: intracellular (GO:0005622)
16 (122)14 (201)16 (295)IPR000717: Proteasome component region PCI
16 (123)18 (134)29 (162)IPR000795: Protein synthesis factor, GTP-bindingMolecular Function: GTP binding (GO:0005525), Biological Process: protein biosynthesis (GO:0006412)
16 (124)14 (206)33 (140)IPR004148: BARMolecular Function: protein binding (GO:0005515), Cellular Component: cytoplasm (GO:0005737)
16 (125)18 (141)27 (172)IPR006594: Lissencephaly type-1-like homology motif
15 (126)40 (48)24 (183)IPR000073: Alpha/beta hydrolase fold
15 (127)16 (158)41 (106)IPR000242: Tyrosine specific protein phosphataseMolecular Function: protein tyrosine phosphatase activity (GO:0004725), Biological Process: protein amino acid dephosphorylation (GO:0006470)
15 (128)9 (293)9 (504)IPR000560: Histidine acid phosphataseMolecular Function: acid phosphatase activity (GO:0003993)
15 (129)28 (74)27 (170)IPR000873: AMP-dependent synthetase and ligaseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolism (GO:0008152)
15 (130)22 (105)18 (263)IPR001320: Ionotropic glutamate receptorMolecular Function: ionotropic glutamate receptor activity (GO:0004970), Molecular Function: glutamate-gated ion channel activity (GO:0005234), Cellular Component: membrane (GO:0016020)
15 (131)18 (137)42 (104)IPR001766: Fork head transcription factorMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
15 (132)9 (300)26 (173)IPR002017: Spectrin repeat
15 (133)16 (168)37 (119)IPR002130: Peptidyl-prolyl cis-trans isomerase, cyclophilin typeBiological Process: protein folding (GO:0006457)
15 (134)12 (235)35 (128)IPR003008: Tubulin/FtsZ, GTPase
15 (135)15 (189)34 (134)IPR004000: Actin/actin-likeMolecular Function: protein binding (GO:0005515)
15 (136)10 (279)13 (377)IPR004273: Dynein heavy chainMolecular Function: microtubule motor activity (GO:0003777), Biological Process: microtubule-based movement (GO:0007018), Cellular Component: dynein complex (GO:0030286)
15 (137)15 (192)22 (217)IPR004841: Amino acid permease-associated regionBiological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
15 (138)13 (222)30 (159)IPR006671: Cyclin, N-terminalBiological Process: regulation of progression through cell cycle (GO:0000074)
15 (139)10 (289)64 (60)IPR008160: Collagen triple helix repeatCellular Component: cytoplasm (GO:0005737), Biological Process: phosphate transport (GO:0006817)
14 (140)11 (244)36 (123)IPR000159: RABiological Process: signal transduction (GO:0007165)
14 (141)21 (112)21 (221)IPR000175: Sodium:neurotransmitter symporterMolecular Function: neurotransmitter:sodium symporter activity (GO:0005328), Cellular Component: integral to plasma membrane (GO:0005887), Biological Process: neurotransmitter transport (GO:0006836), Cellular Component: membrane (GO:0016020)
14 (142)17 (146)5 (811)IPR000412: ABC-2Molecular Function: ATP binding (GO:0005524), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020), Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626)
14 (143)14 (200)28 (167)IPR000569: HECTMolecular Function: ubiquitin-protein ligase activity (GO:0004842), Cellular Component: intracellular (GO:0005622), Biological Process: protein modification (GO:0006464), Biological Process: ubiquitin cycle (GO:0006512)
14 (144)32 (61)9 (505)IPR000734: LipaseMolecular Function: catalytic activity (GO:0003824), Biological Process: lipid metabolism (GO:0006629)
14 (145)12 (232)81 (49)IPR002035: von Willebrand factor, type A
14 (146)20 (125)7 (646)IPR002076: GNS1/SUR4 membrane proteinCellular Component: integral to membrane (GO:0016021)
14 (147)22 (108)40 (111)IPR002350: Proteinase inhibitor I1, Kazal
14 (148)16 (171)25 (182)IPR004161: Elongation factor Tu, domain 2Molecular Function: GTP binding (GO:0005525)
14 (149)10 (285)15 (327)IPR006935: Type III restriction enzyme, res subunitMolecular Function: ATP binding (GO:0005524)
14 (150)14 (208)18 (273)IPR007502: Helicase-associated regionMolecular Function: helicase activity (GO:0004386)
14 (151)12 (242)36 (127)IPR008280: Tubulin/FtsZ, C-terminalMolecular Function: GTPase activity (GO:0003924), Molecular Function: GTP binding (GO:0005525), Cellular Component: protein complex (GO:0043234), Biological Process: protein polymerization (GO:0051258)
14 (152)14 (209)37 (121)IPR011616: bZIP transcription factor, bZIP_1Molecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
13 (153)16 (157)30 (152)IPR000014: PASMolecular Function: signal transducer activity (GO:0004871), Biological Process: signal transduction (GO:0007165)
13 (154)22 (104)23 (194)IPR001140: ABC transporter, transmembrane regionMolecular Function: ATP binding (GO:0005524), Biological Process: transport (GO:0006810), Cellular Component: integral to membrane (GO:0016021), Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626)
13 (155)26 (83)19 (253)IPR001353: 20S proteasome, A and B subunitsMolecular Function: threonine endopeptidase activity (GO:0004298), Cellular Component: proteasome core complex (sensu Eukaryota) (GO:0005839), Biological Process: ubiquitin-dependent protein catabolism (GO:0006511)
13 (156)15 (185)14 (345)IPR001507: Endoglin/CD105 antigen
13 (157)12 (230)25 (179)IPR001610: PAC motifBiological Process: regulation of transcription, DNA-dependent (GO:0006355), Biological Process: signal transduction (GO:0007165)
13 (158)11 (249)30 (156)IPR002049: Laminin-type EGF-likeMolecular Function: structural molecule activity (GO:0005198)
13 (159)15 (188)37 (120)IPR003595: Protein tyrosine phosphatase, catalytic regionMolecular Function: protein tyrosine phosphatase activity (GO:0004725)
13 (160)54 (41)2 (1694)IPR004119: Protein of unknown function DUF227Molecular Function: molecular function unknown (GO:0005554)
13 (161)28 (77) ()IPR004272: Odorant binding proteinMolecular Function: molecular function unknown (GO:0005554)
13 (162)36 (54) ()IPR006170: Pheromone/general odorant binding protein, PBP/GOBPMolecular Function: odorant binding (GO:0005549), Biological Process: transport (GO:0006810)
13 (163)13 (223)29 (166)IPR006689: ARF/SAR superfamilyMolecular Function: GTP binding (GO:0005525)
13 (164)22 (110)40 (113)IPR011497: Protease inhibitor, Kazal-type
13 (165)19 (132)50 (79)IPR011705: BTB/Kelch-associated
13 (166)20 (130) ()IPR012464: Protein of unknown function DUF1676
12 (167)12 (226)41 (107)IPR000340: Dual specificity protein phosphataseBiological Process: protein amino acid dephosphorylation (GO:0006470), Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138)
12 (168)11 (245)19 (249)IPR000403: Phosphatidylinositol 3- and 4-kinase, catalyticMolecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773)
12 (169)14 (199)17 (276)IPR000433: Zinc finger, ZZ-typeMolecular Function: zinc ion binding (GO:0008270)
12 (170)13 (210)20 (237)IPR001159: Double-stranded RNA bindingMolecular Function: double-stranded RNA binding (GO:0003725), Cellular Component: intracellular (GO:0005622)
12 (171)16 (165)12 (389)IPR001199: Cytochrome b5
12 (172)12 (228)22 (211)IPR001357: BRCTCellular Component: intracellular (GO:0005622)
12 (173)14 (204)22 (214)IPR001876: Zinc finger, RanBP2-type
12 (174)10 (271)18 (266)IPR002123: Phospholipid/glycerol acyltransferaseBiological Process: metabolism (GO:0008152), Molecular Function: acyltransferase activity (GO:0008415)
12 (175)12 (234)14 (348)IPR002225: 3-beta hydroxysteroid dehydrogenase/isomeraseMolecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854), Biological Process: steroid biosynthesis (GO:0006694)
12 (176)16 (169)18 (267)IPR002422: Amino acid/polyamine transporter IIMolecular Function: amino acid-polyamine transporter activity (GO:0005279), Biological Process: amino acid transport (GO:0006865), Cellular Component: membrane (GO:0016020)
12 (177)12 (239)87 (41)IPR003877: SPla/RYanodine receptor SPRY
12 (178)9 (313)9 (552)IPR011704: ATPase associated with various cellular activities, AAA_5Molecular Function: ATP binding (GO:0005524), Molecular Function: ATPase activity (GO:0016887)
11 (179)14 (198)23 (191)IPR000086: NUDIX hydrolase
11 (180)6 (410)74 (52)IPR000315: Zinc finger, B-boxCellular Component: intracellular (GO:0005622), Molecular Function: zinc ion binding (GO:0008270)
11 (181)9 (292)17 (275)IPR000408: Regulator of chromosome condensation, RCC1
11 (182)16 (159)54 (69)IPR000436: Sushi/SCR/CCP
11 (183)20 (124)30 (153)IPR000953: ChromoCellular Component: chromatin (GO:0000785), Molecular Function: chromatin binding (GO:0003682), Cellular Component: nucleus (GO:0005634), Biological Process: chromatin assembly or disassembly (GO:0006333)
11 (184)15 (181)36 (124)IPR001007: von Willebrand factor, type C
11 (185)21 (117)22 (213)IPR001594: Zinc finger, DHHC-typeMolecular Function: metal ion binding (GO:0046872)
11 (186)15 (187)18 (265)IPR001932: Protein phosphatase 2C-likeMolecular Function: catalytic activity (GO:0003824)
11 (187)35 (57)14 (347)IPR002213: UDP-glucuronosyl/UDP-glucosyltransferaseBiological Process: metabolism (GO:0008152), Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758)
11 (188)12 (236)51 (76)IPR003131: K+ channel tetramerisationMolecular Function: voltage-gated potassium channel activity (GO:0005249), Biological Process: potassium ion transport (GO:0006813), Cellular Component: voltage-gated potassium channel complex (GO:0008076), Cellular Component: membrane (GO:0016020)
11 (189)13 (217)30 (158)IPR003347: Transcription factor jumonji, jmjC
11 (190)10 (276)24 (186)IPR003577: Ras small GTPase, Ras typeMolecular Function: GTP binding (GO:0005525), Biological Process: small GTPase mediated signal transduction (GO:0007264)
11 (191)12 (237)22 (215)IPR003604: Zinc finger, U1-typeMolecular Function: nucleic acid binding (GO:0003676), Cellular Component: nucleus (GO:0005634), Molecular Function: zinc ion binding (GO:0008270)
11 (192)11 (252)45 (96)IPR003659: Plexin/semaphorin/integrinBiological Process: development (GO:0007275)
11 (193)7 (385)10 (480)IPR003958: Transcription factor CBF/NF-Y/archaeal histoneMolecular Function: DNA binding (GO:0003677)
11 (194)11 (255)10 (485)IPR004344: Tubulin-tyrosine ligaseMolecular Function: tubulin-tyrosine ligase activity (GO:0004835), Biological Process: protein modification (GO:0006464)
11 (195)8 (349)23 (205)IPR008250: E1-E2 ATPase-associated regionMolecular Function: ATP binding (GO:0005524), Cellular Component: membrane (GO:0016020), Molecular Function: hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances (GO:0016820)
11 (196)13 (224)17 (293)IPR011709: Protein of unknown function DUF1605Molecular Function: ATP binding (GO:0005524), Molecular Function: ATP-dependent helicase activity (GO:0008026)
10 (197)8 (315)19 (248)IPR000313: PWWP
10 (198)10 (263)25 (178)IPR000337: GPCR, family 3, metabotropic glutamate receptor-likeMolecular Function: metabotropic glutamate, GABA-B-like receptor activity (GO:0008067), Cellular Component: membrane (GO:0016020)
10 (199)8 (316)31 (147)IPR000342: Regulator of G protein signallingMolecular Function: signal transducer activity (GO:0004871)
10 (200)22 (102)45 (92)IPR000832: GPCR, family 2, secretin-likeMolecular Function: G-protein coupled receptor activity (GO:0004930), Cellular Component: membrane (GO:0016020)
10 (201)24 (95)22 (208)IPR000834: Peptidase M14, carboxypeptidase AMolecular Function: carboxypeptidase A activity (GO:0004182), Biological Process: proteolysis and peptidolysis (GO:0006508)
10 (202)15 (183)22 (209)IPR001148: Carbonic anhydrase, eukaryoticMolecular Function: carbonate dehydratase activity (GO:0004089), Biological Process: one-carbon compound metabolism (GO:0006730), Molecular Function: zinc ion binding (GO:0008270)
10 (203)16 (164)23 (195)IPR001173: Glycosyl transferase, family 2
10 (204)16 (166)7 (634)IPR001223: Glycoside hydrolase, family 18Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553), Biological Process: carbohydrate metabolism (GO:0005975)
10 (205)35 (55)81 (47)IPR001304: C-type lectinMolecular Function: sugar binding (GO:0005529)
10 (206)6 (431)40 (110)IPR001590: Peptidase M12B, ADAM/reprolysinMolecular Function: metalloendopeptidase activity (GO:0004222), Biological Process: proteolysis and peptidolysis (GO:0006508)
10 (207)14 (203)17 (286)IPR001753: Enoyl-CoA hydratase/isomeraseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolism (GO:0008152)
10 (208)22 (107)13 (370)IPR001930: Peptidase M1, membrane alanine aminopeptidaseMolecular Function: membrane alanyl aminopeptidase activity (GO:0004179), Biological Process: proteolysis and peptidolysis (GO:0006508)
10 (209)7 (374)20 (240)IPR002085: Alcohol dehydrogenase superfamily, zinc-containingMolecular Function: zinc ion binding (GO:0008270), Molecular Function: oxidoreductase activity (GO:0016491)
10 (210)10 (272)10 (470)IPR002129: Pyridoxal-dependent decarboxylaseBiological Process: amino acid metabolism (GO:0006520), Molecular Function: carboxy-lyase activity (GO:0016831)
10 (211)13 (215)17 (289)IPR002423: Chaperonin Cpn60/TCP-1Molecular Function: protein binding (GO:0005515), Molecular Function: ATP binding (GO:0005524), Biological Process: cellular protein metabolism (GO:0044267)
10 (212)13 (216)26 (174)IPR002999: TudorMolecular Function: nucleic acid binding (GO:0003676)
10 (213)10 (274)12 (395)IPR003029: RNA binding S1Molecular Function: RNA binding (GO:0003723)
10 (214)10 (277)23 (202)IPR003607: Metal-dependent phosphohydrolase, HD regionMolecular Function: catalytic activity (GO:0003824)
10 (215)10 (280)15 (323)IPR004839: Aminotransferase, class I and IIBiological Process: biosynthesis (GO:0009058), Molecular Function: transferase activity, transferring nitrogenous groups (GO:0016769)
10 (216)12 (240)42 (105)IPR005135: Endonuclease/exonuclease/phosphatase
10 (217)11 (256)31 (149)IPR006020: Phosphotyrosine interaction region
10 (218)29 (73) ()IPR006625: Insect pheromone/odorant binding protein PhBP
10 (219)10 (284)22 (219)IPR006688: ADP-ribosylation factorMolecular Function: GTP binding (GO:0005525)
9 (220)10 (265)13 (364)IPR000555: Mov34/MPN/PAD-1
9 (221)8 (320)10 (447)IPR000594: UBA/THIF-type NAD/FAD binding foldMolecular Function: catalytic activity (GO:0003824)
9 (222)12 (227)21 (223)IPR000727: Target SNARE coiled-coil region
9 (223)7 (363)32 (142)IPR001164: Arf GTPase activating proteinBiological Process: regulation of GTPase activity (GO:0043087)
9 (224)6 (427)11 (414)IPR001258: NHL repeat
9 (225)11 (248)22 (212)IPR001395: Aldo/keto reductaseMolecular Function: oxidoreductase activity (GO:0016491)
9 (226)8 (327)32 (143)IPR001496: SOCS protein, C-terminalBiological Process: intracellular signaling cascade (GO:0007242)
9 (227)16 (167)11 (417)IPR001734: Na+/solute symporterMolecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
9 (228)10 (269)10 (467)IPR002007: Animal haem peroxidaseMolecular Function: peroxidase activity (GO:0004601)
9 (229)10 (270)8 (577)IPR002068: Heat shock protein Hsp20
9 (230)11 (250)19 (255)IPR002086: Aldehyde dehydrogenaseBiological Process: metabolism (GO:0008152), Molecular Function: oxidoreductase activity (GO:0016491)
9 (231)12 (233)3 (1246)IPR002159: CD36 antigenBiological Process: cell adhesion (GO:0007155), Cellular Component: membrane (GO:0016020)
9 (232)8 (331)8 (578)IPR002300: Aminoacyl-tRNA synthetase, class IaMolecular Function: tRNA ligase activity (GO:0004812), Molecular Function: ATP binding (GO:0005524), Biological Process: tRNA aminoacylation for protein translation (GO:0006418)
9 (233)9 (301)11 (420)IPR002314: tRNA synthetase, class II (G, H, P and S)Molecular Function: tRNA ligase activity (GO:0004812), Molecular Function: ATP binding (GO:0005524), Biological Process: tRNA aminoacylation for protein translation (GO:0006418)
9 (234)4 (654)13 (375)IPR003616: SET-related region
9 (235)8 (338)20 (244)IPR004012: RUN
9 (236)11 (254)10 (484)IPR004274: NLI interacting factor
9 (237)10 (282)8 (602)IPR005804: Fatty acid desaturaseMolecular Function: oxidoreductase activity (GO:0016491)
9 (238)17 (150)21 (230)IPR006076: FAD dependent oxidoreductaseBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
9 (239)6 (472)14 (357)IPR006560: AWS
9 (240)51 (42)5 (915)IPR006578: MADF
9 (241)9 (310)26 (176)IPR008145: Guanylate kinase/L-type calcium channel region
9 (242)15 (197)12 (401)IPR008191: Maternal tudor protein
9 (243)9 (312)10 (494)IPR011547: Sulphate transporterMolecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: integral to membrane (GO:0016021)
9 (244)16 (176)7 (693)IPR011583: Chitinase IIMolecular Function: chitinase activity (GO:0004568), Biological Process: chitin catabolism (GO:0006032)
8 (245)3 (726)6 (699)IPR000092: Polyprenyl synthetaseBiological Process: isoprenoid biosynthesis (GO:0008299)
8 (246)6 (413)24 (184)IPR000413: Integrins alpha chainBiological Process: cell adhesion (GO:0007155), Biological Process: cell-matrix adhesion (GO:0007160), Cellular Component: integrin complex (GO:0008305)
8 (247)8 (317)29 (161)IPR000418: EtsMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
8 (248)17 (147)15 (308)IPR000637: HMG-I and HMG-Y, DNA-binding
8 (249)21 (116)7 (627)IPR000718: Peptidase M13, neprilysinMolecular Function: neprilysin activity (GO:0004245), Biological Process: proteolysis and peptidolysis (GO:0006508), Cellular Component: membrane (GO:0016020)
8 (250)10 (268)15 (311)IPR000917: SulfataseBiological Process: metabolism (GO:0008152), Molecular Function: sulfuric ester hydrolase activity (GO:0008484)
8 (251)9 (296)10 (454)IPR000994: Peptidase M24Biological Process: proteolysis and peptidolysis (GO:0006508), Molecular Function: metalloexopeptidase activity (GO:0008235)
8 (252)11 (247)11 (413)IPR001107: Band 7 protein
8 (253)8 (323)14 (341)IPR001206: Diacylglycerol kinase, catalytic regionMolecular Function: diacylglycerol kinase activity (GO:0004143), Biological Process: protein kinase C activation (GO:0007205)
8 (254)7 (364)8 (567)IPR001208: MCMMolecular Function: DNA binding (GO:0003677), Molecular Function: ATP binding (GO:0005524), Biological Process: DNA replication initiation (GO:0006270), Molecular Function: DNA-dependent ATPase activity (GO:0008094)
8 (255)6 (425)8 (568)IPR001236: Lactate/malate dehydrogenaseBiological Process: tricarboxylic acid cycle intermediate metabolism (GO:0006100), Molecular Function: oxidoreductase activity (GO:0016491)
8 (256)15 (184)12 (390)IPR001494: Importin-beta, N-terminalBiological Process: protein-nucleus import, docking (GO:0000059), Cellular Component: nucleus (GO:0005634), Cellular Component: nuclear pore (GO:0005643), Cellular Component: cytoplasm (GO:0005737), Molecular Function: protein transporter activity (GO:0008565)
8 (257)7 (370)12 (391)IPR001529: DNA-directed RNA polymerase, M/15 kDa subunitMolecular Function: DNA binding (GO:0003677), Molecular Function: DNA-directed RNA polymerase activity (GO:0003899), Biological Process: transcription (GO:0006350)
8 (258)6 (436)20 (238)IPR001763: Rhodanese-like
8 (259)6 (441)20 (239)IPR002073: 3'5'-cyclic nucleotide phosphodiesteraseMolecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114), Biological Process: signal transduction (GO:0007165)
8 (260)8 (330)29 (164)IPR002165: PlexinMolecular Function: receptor activity (GO:0004872), Cellular Component: membrane (GO:0016020)
8 (261)4 (643)10 (474)IPR002919: Protease inhibitor I8, cysteine-rich trypsin inhibitor-like
8 (262)5 (534)10 (477)IPR003392: PatchedMolecular Function: hedgehog receptor activity (GO:0008158), Cellular Component: membrane (GO:0016020)
8 (263)6 (456)6 (753)IPR003395: SMC protein, N-terminalMolecular Function: ATP binding (GO:0005524), Cellular Component: chromosome (GO:0005694), Biological Process: chromosome organization and biogenesis (GO:0051276)
8 (264)7 (383)20 (243)IPR003594: ATP-binding region, ATPase-likeMolecular Function: ATP binding (GO:0005524)
8 (265)9 (305)14 (349)IPR003689: Zinc/iron permeaseCellular Component: membrane (GO:0016020), Biological Process: metal ion transport (GO:0030001), Molecular Function: metal ion transporter activity (GO:0046873)
8 (266)8 (337)18 (269)IPR003903: Ubiquitin interacting motif
8 (267)39 (51)23 (203)IPR004045: Glutathione S-transferase, N-terminal
8 (268)8 (344)18 (271)IPR005824: KOW
8 (269)7 (393)13 (380)IPR006055: ExonucleaseMolecular Function: exonuclease activity (GO:0004527), Cellular Component: intracellular (GO:0005622)
8 (270)10 (283)11 (434)IPR006090: Acyl-CoA dehydrogenase, C-terminalBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
8 (271)13 (219)15 (324)IPR006091: Acyl-CoA dehydrogenase, central regionMolecular Function: acyl-CoA dehydrogenase activity (GO:0003995), Biological Process: electron transport (GO:0006118)
8 (272)6 (471)18 (272)IPR006212: Furin-like repeat
8 (273)9 (307)15 (325)IPR006553: Leucine-rich repeat, cysteine-containing subtype
8 (274)9 (308)11 (437)IPR006575: RWD
8 (275)20 (129)1 (2460)IPR006631: Protein of unknown function DM4/12
8 (276)7 (397)7 (687)IPR007863: Peptidase M16, C-terminal
8 (277)18 (142)7 (689)IPR008753: Peptidase M13Biological Process: proteolysis and peptidolysis (GO:0006508), Molecular Function: metallopeptidase activity (GO:0008237)
8 (278)17 (155)9 (551)IPR011022: Arrestin, C-terminal
7 (279)10 (261)15 (303)IPR000033: Low-density lipoprotein receptor, YWTD repeatCellular Component: membrane (GO:0016020)
7 (280)5 (485)7 (619)IPR000061: SWAP/SurpMolecular Function: RNA binding (GO:0003723), Biological Process: RNA processing (GO:0006396)
7 (281)6 (406)9 (497)IPR000089: Biotin/lipoyl attachment
7 (282)29 (70)34 (130)IPR000215: Proteinase inhibitor I4, serpinMolecular Function: serine-type endopeptidase inhibitor activity (GO:0004867)
7 (283)5 (491)21 (222)IPR000421: Coagulation factor 5/8 type, C-terminalBiological Process: cell adhesion (GO:0007155)
7 (284)8 (318)33 (136)IPR000488: DeathMolecular Function: protein binding (GO:0005515), Biological Process: signal transduction (GO:0007165)
7 (285)6 (416)5 (817)IPR000640: Elongation factor G, C-terminalMolecular Function: GTP binding (GO:0005525)
7 (286)5 (494)17 (277)IPR000644: CBS
7 (287)6 (417)12 (387)IPR000679: Zinc finger, GATA-typeMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
7 (288)9 (294)5 (821)IPR000760: Inositol monophosphataseMolecular Function: inositol or phosphatidylinositol phosphatase activity (GO:0004437)
7 (289)10 (267)31 (148)IPR000863: SulfotransferaseMolecular Function: sulfotransferase activity (GO:0008146)
7 (290)9 (295)6 (711)IPR000866: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen
7 (291)7 (359)9 (509)IPR000938: CAP-Gly
7 (292)6 (421)10 (456)IPR001025: Bromo adjacent regionMolecular Function: DNA binding (GO:0003677)
7 (293)5 (504)18 (261)IPR001060: Cdc15/Fes/CIP4
7 (294)6 (423)18 (262)IPR001093: IMP dehydrogenase/GMP reductaseMolecular Function: catalytic activity (GO:0003824)
7 (295)8 (322)19 (252)IPR001179: Peptidylprolyl isomerase, FKBP-typeBiological Process: protein folding (GO:0006457)
7 (296)6 (426)7 (635)IPR001247: 3' exoribonucleaseMolecular Function: 3'-5'-exoribonuclease activity (GO:0000175), Molecular Function: RNA binding (GO:0003723), Biological Process: RNA processing (GO:0006396)
7 (297)7 (368)9 (517)IPR001375: Peptidase S9, prolyl oligopeptidase active site regionBiological Process: proteolysis and peptidolysis (GO:0006508), Molecular Function: serine-type peptidase activity (GO:0008236)
7 (298)9 (299)9 (520)IPR001523: Paired box protein, N-terminalCellular Component: nucleus (GO:0005634), Biological Process: development (GO:0007275)
7 (299)6 (433)13 (369)IPR001606: AT-rich interaction regionMolecular Function: DNA binding (GO:0003677), Cellular Component: intracellular (GO:0005622)
7 (300)7 (372)36 (125)IPR001839: Transforming growth factor betaMolecular Function: growth factor activity (GO:0008083)
7 (301)25 (91)8 (575)IPR001873: Na+ channel, amiloride-sensitiveMolecular Function: sodium channel activity (GO:0005272), Biological Process: sodium ion transport (GO:0006814), Cellular Component: membrane (GO:0016020)
7 (302)8 (329)29 (163)IPR001895: Guanine-nucleotide dissociation stimulator CDC25Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085), Biological Process: intracellular signaling cascade (GO:0007242)
7 (303)2 (1023)7 (644)IPR001991: Sodium:dicarboxylate symporterBiological Process: dicarboxylic acid transport (GO:0006835), Cellular Component: membrane (GO:0016020), Molecular Function: sodium:dicarboxylate symporter activity (GO:0017153)
7 (304)7 (376)13 (371)IPR002553: Adaptin, N-terminal
7 (305)10 (273)30 (157)IPR002909: Cell surface receptor IPT/TIG
7 (306)7 (379)9 (531)IPR003014: N/apple PAN
7 (307)5 (531)19 (256)IPR003034: DNA-binding SAPMolecular Function: DNA binding (GO:0003677)
7 (308)7 (380)8 (588)IPR003107: RNA-processing protein, HAT helixCellular Component: intracellular (GO:0005622), Biological Process: RNA processing (GO:0006396)
7 (309)8 (335)15 (321)IPR003409: MORN motif
7 (310)6 (457)23 (201)IPR003578: Ras small GTPase, Rho typeMolecular Function: GTP binding (GO:0005525), Biological Process: small GTPase mediated signal transduction (GO:0007264)
7 (311)6 (458)13 (374)IPR003603: Leucine-rich-associated
7 (312)8 (339)10 (482)IPR004156: Organic anion transporter polypeptide OATPMolecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
7 (313)7 (388)18 (270)IPR004160: Elongation factor Tu, C-terminalMolecular Function: GTP binding (GO:0005525)
7 (314)15 (191)1 (2329)IPR004262: Male sterility protein
7 (315)7 (390)11 (430)IPR004365: nucleic acid binding, OB-fold, tRNA/helicase-typeMolecular Function: nucleic acid binding (GO:0003676)
7 (316)8 (340)9 (539)IPR004837: Sodium/calcium exchanger membrane regionCellular Component: integral to membrane (GO:0016021)
7 (317)8 (341)3 (1318)IPR005018: DOMONMolecular Function: dopamine beta-monooxygenase activity (GO:0004500), Biological Process: catecholamine metabolism (GO:0006584)
7 (318)21 (119)17 (291)IPR005123: 2OG-Fe(II) oxygenase
7 (319)6 (464)8 (600)IPR005475: Transketolase, central region
7 (320)7 (392)19 (258)IPR005817: Wnt superfamilyMolecular Function: signal transducer activity (GO:0004871), Cellular Component: extracellular region (GO:0005576), Biological Process: frizzled-2 signaling pathway (GO:0007223), Biological Process: development (GO:0007275)
7 (321)14 (207)7 (679)IPR006047: Alpha amylase, catalytic regionMolecular Function: alpha-amylase activity (GO:0004556), Biological Process: carbohydrate metabolism (GO:0005975)
7 (322)17 (151)14 (355)IPR006186: Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphataseMolecular Function: hydrolase activity (GO:0016787)
7 (323)11 (257)10 (487)IPR006569: Regulation of nuclear pre-mRNA protein
7 (324)8 (345)8 (603)IPR006595: CTLH, C-terminal to LisH motif
7 (325)6 (473)11 (439)IPR006612: Zinc finger, C2CH-typeMolecular Function: nucleic acid binding (GO:0003676)
7 (326)9 (309)1 (2670)IPR007889: Helix-turn-helix, PsqMolecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634)
7 (327)7 (398)20 (246)IPR008144: Guanylate kinase
7 (328)5 (566)15 (328)IPR008197: Whey acidic protein, core region
7 (329)17 (154)9 (550)IPR011021: Arrestin, N-terminal
6 (330)5 (486)10 (445)IPR000209: Peptidase S8 and S53, subtilisin, kexin, sedolisinMolecular Function: subtilase activity (GO:0004289), Biological Process: proteolysis and peptidolysis (GO:0006508)
6 (331)10 (264)14 (331)IPR000348: emp24/gp25L/p24Biological Process: intracellular protein transport (GO:0006886), Molecular Function: protein carrier activity (GO:0008320), Cellular Component: membrane (GO:0016020)
6 (332)7 (354)15 (306)IPR000425: Major intrinsic proteinMolecular Function: transporter activity (GO:0005215), Biological Process: transport (GO:0006810), Cellular Component: membrane (GO:0016020)
6 (333)7 (356)7 (626)IPR000577: Carbohydrate kinase, FGGYBiological Process: carbohydrate metabolism (GO:0005975)
6 (334)5 (495)19 (250)IPR000651: Guanine nucleotide exchange factor for Ras-like GTPases, N-terminalMolecular Function: guanyl-nucleotide exchange factor activity (GO:0005085), Biological Process: small GTPase mediated signal transduction (GO:0007264)
6 (335)11 (246)15 (309)IPR000668: Peptidase C1A, papainBiological Process: proteolysis and peptidolysis (GO:0006508), Molecular Function: cysteine-type peptidase activity (GO:0008234)
6 (336)14 (202)24 (185)IPR000772: Ricin B lectin
6 (337)4 (596)8 (561)IPR000850: Adenylate kinaseMolecular Function: ATP binding (GO:0005524), Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0006139), Molecular Function: nucleotide kinase activity (GO:0019201)
6 (338)6 (419)16 (296)IPR000904: SEC7-like
6 (339)4 (598)15 (310)IPR000909: Phosphatidylinositol-specific phospholipase C, X regionMolecular Function: phospholipase C activity (GO:0004629), Biological Process: signal transduction (GO:0007165), Biological Process: intracellular signaling cascade (GO:0007242)
6 (340)9 (297)14 (337)IPR001012: UBX
6 (341)6 (420)6 (713)IPR001017: Dehydrogenase, E1 componentBiological Process: metabolism (GO:0008152), Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624)
6 (342)7 (361)16 (297)IPR001019: Guanine nucleotide binding protein (G-protein), alpha subunitMolecular Function: signal transducer activity (GO:0004871), Biological Process: G-protein coupled receptor protein signaling pathway (GO:0007186), Molecular Function: guanyl nucleotide binding (GO:0019001)
6 (343)15 (182)11 (412)IPR001023: Heat shock protein Hsp70Molecular Function: ATP binding (GO:0005524)
6 (344)2 (983)6 (715)IPR001087: Lipolytic enzyme, G-D-S-LBiological Process: lipid metabolism (GO:0006629), Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788)
6 (345)8 (324)10 (459)IPR001279: Beta-lactamase-like
6 (346)8 (325)8 (571)IPR001327: FAD-dependent pyridine nucleotide-disulphide oxidoreductaseBiological Process: electron transport (GO:0006118), Molecular Function: disulfide oxidoreductase activity (GO:0015036)
6 (347)7 (366)14 (344)IPR001345: Phosphoglycerate/bisphosphoglycerate mutaseMolecular Function: catalytic activity (GO:0003824), Biological Process: metabolism (GO:0008152)
6 (348)7 (367)9 (515)IPR001373: CullinBiological Process: cell cycle (GO:0007049)
6 (349)5 (507)9 (516)IPR001374: Single-stranded nucleic acid binding R3HMolecular Function: nucleic acid binding (GO:0003676)
6 (350)6 (429)13 (368)IPR001433: Oxidoreductase FAD/NAD(P)-bindingBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
6 (351)5 (511)5 (829)IPR001451: Bacterial transferase hexapeptide repeat
6 (352)4 (619)3 (1222)IPR001540: Glycoside hydrolase, family 20Molecular Function: beta-N-acetylhexosaminidase activity (GO:0004563), Biological Process: carbohydrate metabolism (GO:0005975)
6 (353)8 (328)17 (285)IPR001699: Transcription factor, T-boxMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
6 (354)3 (769)14 (346)IPR001711: Phosphatidylinositol-specific phospholipase C, Y domainMolecular Function: phosphoinositide phospholipase C activity (GO:0004435), Biological Process: lipid metabolism (GO:0006629), Biological Process: signal transduction (GO:0007165), Biological Process: intracellular signaling cascade (GO:0007242)
6 (355)7 (371)7 (641)IPR001737: Ribosomal RNA adenine methylase transferaseBiological Process: rRNA modification (GO:0000154), Molecular Function: rRNA (adenine-N6,N6-)-dimethyltransferase activity (GO:0000179), Molecular Function: rRNA methyltransferase activity (GO:0008649)
6 (356)5 (515)23 (198)IPR001762: Disintegrin
6 (357)5 (517)16 (298)IPR001846: von Willebrand factor, type D
6 (358)5 (518)15 (315)IPR001936: Ras GTPase-activating protein
6 (359)2 (1026)3 (1240)IPR002015: Proteasome/cyclosome, regulatory subunitBiological Process: regulation of progression through cell cycle (GO:0000074)
6 (360)7 (375)9 (526)IPR002524: Cation efflux proteinBiological Process: cation transport (GO:0006812), Molecular Function: cation transporter activity (GO:0008324), Cellular Component: membrane (GO:0016020)
6 (361)9 (302)13 (372)IPR002659: Glycosyl transferase, family 31Biological Process: protein amino acid glycosylation (GO:0006486), Molecular Function: galactosyltransferase activity (GO:0008378), Cellular Component: membrane (GO:0016020)
6 (362)6 (448)5 (849)IPR002877: Ribosomal RNA methyltransferase RrmJ/FtsJ
6 (363)18 (140)7 (654)IPR002933: Peptidase M20Biological Process: proteolysis and peptidolysis (GO:0006508), Molecular Function: metallopeptidase activity (GO:0008237)
6 (364)8 (333)7 (655)IPR002937: Amine oxidaseBiological Process: electron transport (GO:0006118), Molecular Function: oxidoreductase activity (GO:0016491)
6 (365)5 (530)8 (585)IPR003000: Silent information regulator protein Sir2Molecular Function: DNA binding (GO:0003677), Cellular Component: chromatin silencing complex (GO:0005677), Biological Process: chromatin silencing (GO:0006342), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
6 (366)8 (334)8 (586)IPR003010: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferaseBiological Process: nitrogen compound metabolism (GO:0006807), Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810)
6 (367)6 (450)13 (373)IPR003104: Actin-binding FH2Molecular Function: actin binding (GO:0003779), Biological Process: cell organization and biogenesis (GO:0016043)
6 (368)6 (453)7 (658)IPR003126: Zinc finger, N-recogninMolecular Function: ubiquitin-protein ligase activity (GO:0004842), Biological Process: ubiquitin cycle (GO:0006512)
6 (369)6 (455)12 (397)IPR003323: Ovarian tumour, otubain
6 (370)4 (651)7 (661)IPR003405: Structural maintenance of chromosome protein SMC, C-terminalMolecular Function: ATP binding (GO:0005524), Cellular Component: chromosome (GO:0005694), Biological Process: chromosome organization and biogenesis (GO:0051276)
6 (371)6 (459)7 (665)IPR003609: Apple-like
6 (372)5 (537)7 (666)IPR003613: U boxCellular Component: ubiquitin ligase complex (GO:0000151), Molecular Function: ubiquitin-protein ligase activity (GO:0004842), Biological Process: protein ubiquitination (GO:0016567)
6 (373)12 (238)11 (428)IPR003650: OrangeMolecular Function: DNA binding (GO:0003677), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
6 (374)10 (278)10 (479)IPR003890: Initiation factor eIF-4 gamma, middleMolecular Function: RNA binding (GO:0003723)
6 (375)4 (656)14 (350)IPR003954: RNA recognition, region 1Molecular Function: nucleic acid binding (GO:0003676)
6 (376)5 (541)16 (300)IPR004014: Cation transporting ATPase, N-terminalBiological Process: cation transport (GO:0006812), Molecular Function: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism (GO:0015662), Cellular Component: membrane (GO:0016020)
6 (377)6 (461)22 (216)IPR004038: Ribosomal protein L7Ae/L30e/S12e/Gadd45
6 (378)32 (64)21 (229)IPR004046: Glutathione S-transferase, C-terminal
6 (379)7 (387)10 (481)IPR004154: Anticodon-bindingMolecular Function: tRNA ligase activity (GO:0004812), Molecular Function: ATP binding (GO:0005524), Biological Process: protein biosynthesis (GO:0006412)
6 (380)6 (462)14 (351)IPR004367: Cyclin, C-terminalBiological Process: regulation of progression through cell cycle (GO:0000074), Cellular Component: nucleus (GO:0005634)
6 (381)8 (342)9 (540)IPR005024: Snf7Molecular Function: molecular function unknown (GO:0005554)
6 (382)5 (553)5 (899)IPR005814: Aminotransferase class-IIIMolecular Function: transaminase activity (GO:0008483), Molecular Function: pyridoxal phosphate binding (GO:0030170)
6 (383)6 (467)14 (354)IPR006068: Cation transporting ATPase, C-terminalBiological Process: cation transport (GO:0006812), Molecular Function: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism (GO:0015662), Cellular Component: membrane (GO:0016020)
6 (384)6 (468)9 (542)IPR006092: Acyl-CoA dehydrogenase, N-terminalMolecular Function: acyl-CoA dehydrogenase activity (GO:0003995), Biological Process: electron transport (GO:0006118)
6 (385)3 (857)5 (905)IPR006204: GHMP kinaseMolecular Function: ATP binding (GO:0005524), Molecular Function: kinase activity (GO:0016301), Biological Process: phosphorylation (GO:0016310)
6 (386)24 (99)15 (326)IPR006620: Prolyl 4-hydroxylase, alpha subunitMolecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (GO:0016706), Biological Process: protein metabolism (GO:0019538)
6 (387)15 (194) ()IPR006621: Nose resistant to fluoxetine-4, N-terminal
6 (388)16 (174)16 (301)IPR006629: LPS-induced tumor necrosis factor alpha factor
6 (389)7 (396)13 (383)IPR007123: Gelsolin region
6 (390)10 (286)3 (1399)IPR007248: Mpv17/PMP22Cellular Component: integral to membrane (GO:0016021)
6 (391)4 (701)3 (1430)IPR008257: Peptidase M19, renal dipeptidaseMolecular Function: membrane dipeptidase activity (GO:0004237), Biological Process: proteolysis and peptidolysis (GO:0006508), Molecular Function: dipeptidyl-peptidase activity (GO:0008239)
6 (392)4 (706)22 (220)IPR010294: ADAM-TS Spacer 1Molecular Function: metalloendopeptidase activity (GO:0004222), Cellular Component: extracellular matrix (GO:0031012)
6 (393)5 (572)13 (384)IPR010569: Myotubularin-relatedMolecular Function: inositol or phosphatidylinositol phosphatase activity (GO:0004437), Biological Process: phospholipid dephosphorylation (GO:0046839)
6 (394)4 (709) ()IPR010629: Insect allergen related
5 (395)8 (314)23 (189)IPR000024: Frizzled CRD region
5 (396)4 (576)7 (618)IPR000034: Laminin B
5 (397)6 (407)14 (329)IPR000095: PAK-box/P21-Rho-binding
5 (398)3 (731)13 (363)IPR000156: RanBP1
5 (399)4 (578)22 (206)IPR000164: Histone H3Cellular Component: nucleosome (GO:0000786), Molecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: nucleosome assembly (GO:0006334), Biological Process: chromosome organization and biogenesis (sensu Eukaryota) (GO:0007001)
5 (400)6 (409)9 (500)IPR000300: Inositol polyphosphate related phosphataseMolecular Function: inositol or phosphatidylinositol phosphatase activity (GO:0004437)
5 (401)10 (262)15 (305)IPR000326: Phosphoesterase, PA-phosphatase related
5 (402)4 (583)9 (501)IPR000331: Rap/ran-GAP
5 (403)5 (490)6 (705)IPR000409: Beige/BEACH
5 (404)6 (414)5 (813)IPR000435: TektinBiological Process: microtubule cytoskeleton organization and biogenesis (GO:0000226), Cellular Component: microtubule (GO:0005874)
5 (405)5 (492)5 (814)IPR000462: CDP-alcohol phosphatidyltransferaseBiological Process: phospholipid biosynthesis (GO:0008654)
5 (406)2 (948)8 (558)IPR000533: Tropomyosin
5 (407)2 (949)33 (137)IPR000566: Lipocalin-related protein and Bos/Can/Equ allergenMolecular Function: binding (GO:0005488)
5 (408)6 (415)20 (235)IPR000591: Pleckstrin/ G-protein, interacting regionBiological Process: intracellular signaling cascade (GO:0007242)
5 (409)5 (498)11 (411)IPR000697: EVH1
5 (410)5 (499)9 (506)IPR000756: Diacylglycerol kinase accessory regionMolecular Function: diacylglycerol kinase activity (GO:0004143), Biological Process: protein kinase C activation (GO:0007205)
5 (411)6 (418)10 (450)IPR000836: PhosphoribosyltransferaseBiological Process: nucleoside metabolism (GO:0009116)
5 (412)4 (597)9 (507)IPR000857: Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4Cellular Component: cytoskeleton (GO:0005856)
5 (413)7 (358) ()IPR000896: Arthropod hemocyanin/insect LSPMolecular Function: oxygen transporter activity (GO:0005344), Biological Process: transport (GO:0006810)
5 (414)4 (602)2 (1557)IPR001117: Multicopper oxidase, type 1Molecular Function: copper ion binding (GO:0005507)
5 (415)6 (424)8 (565)IPR001132: Dwarfin proteinCellular Component: intracellular (GO:0005622), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
5 (416)4 (603)14 (340)IPR001180: Citron-likeMolecular Function: small GTPase regulator activity (GO:0005083)
5 (417)4 (611)9 (514)IPR001298: Filamin/ABP280 repeat
5 (418)4 (617)10 (460)IPR001370: Proteinase inhibitor I32, inhibitor of apoptosisCellular Component: intracellular (GO:0005622), Biological Process: anti-apoptosis (GO:0006916)
5 (419)5 (509)9 (518)IPR001388: SynaptobrevinCellular Component: integral to membrane (GO:0016021), Biological Process: vesicle-mediated transport (GO:0016192)
5 (420)4 (618)10 (461)IPR001392: Clathrin adaptor complex, medium chainBiological Process: intracellular protein transport (GO:0006886), Cellular Component: clathrin vesicle coat (GO:0030125)
5 (421)6 (428)13 (367)IPR001401: DynaminMolecular Function: GTPase activity (GO:0003924), Molecular Function: GTP binding (GO:0005525)
5 (422)1 (1517)4 (1021)IPR001525: C-5 cytosine-specific DNA methylaseMolecular Function: DNA binding (GO:0003677), Biological Process: DNA methylation (GO:0006306)
5 (423)5 (513)7 (639)IPR001619: Sec1-like proteinBiological Process: vesicle docking during exocytosis (GO:0006904), Biological Process: vesicle-mediated transport (GO:0016192)
5 (424)6 (434)30 (155)IPR001627: Semaphorin/CD100 antigen
5 (425)4 (627)2 (1590)IPR001747: Lipid transport protein, N-terminalMolecular Function: lipid transporter activity (GO:0005319), Biological Process: lipid transport (GO:0006869)
5 (426)5 (519)12 (393)IPR002083: MATH
5 (427)2 (1033)25 (181)IPR002119: Histone H2ACellular Component: nucleosome (GO:0000786), Molecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: nucleosome assembly (GO:0006334), Biological Process: chromosome organization and biogenesis (sensu Eukaryota) (GO:0007001)
5 (428)6 (443)5 (838)IPR002125: CMP/dCMP deaminase, zinc-bindingMolecular Function: zinc ion binding (GO:0008270), Molecular Function: hydrolase activity (GO:0016787)
5 (429)6 (444)7 (648)IPR002155: Thiolase
5 (430)25 (92)17 (288)IPR002223: Proteinase inhibitor I2, Kunitz metazoaMolecular Function: serine-type endopeptidase inhibitor activity (GO:0004867)
5 (431)5 (522)6 (739)IPR002469: Peptidase S9B, dipeptidylpeptidase IV N-terminalMolecular Function: dipeptidyl-peptidase IV activity (GO:0004274), Biological Process: proteolysis and peptidolysis (GO:0006508), Cellular Component: membrane (GO:0016020)
5 (432)11 (251)4 (1048)IPR002502: N-acetylmuramoyl-L-alanine amidase, family 2Molecular Function: N-acetylmuramoyl-L-alanine amidase activity (GO:0008745), Biological Process: peptidoglycan catabolism (GO:0009253)
5 (433)5 (525)5 (844)IPR002562: 3'-5' exonucleaseMolecular Function: nucleic acid binding (GO:0003676), Cellular Component: intracellular (GO:0005622), Molecular Function: 3'-5' exonuclease activity (GO:0008408)
5 (434)7 (377)9 (527)IPR002610: Rhomboid-like protein
5 (435)3 (792)9 (529)IPR002857: Zinc finger, CXXC-typeMolecular Function: DNA binding (GO:0003677), Molecular Function: zinc ion binding (GO:0008270)
5 (436)9 (304)9 (530)IPR002939: Chaperone DnaJ, C-terminalBiological Process: protein folding (GO:0006457), Molecular Function: unfolded protein binding (GO:0051082)
5 (437)6 (451)15 (320)IPR003118: Sterile alpha motif/pointedMolecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634)
5 (438)6 (452)19 (257)IPR003124: Actin-binding WH2
5 (439)5 (532)5 (857)IPR003152: PIK-related kinase, FATC
5 (440)5 (533)8 (592)IPR003307: eIF4-gamma/eIF5/eIF2-epsilonMolecular Function: translation initiation factor activity (GO:0003743), Biological Process: regulation of translational initiation (GO:0006446)
5 (441)7 (382)5 (863)IPR003397: Mitochondrial import inner membrane translocase, subunit Tim17/22Cellular Component: mitochondrial inner membrane (GO:0005743), Molecular Function: protein transporter activity (GO:0008565), Biological Process: protein transport (GO:0015031)
5 (442)5 (538)12 (398)IPR003619: Dwarfin protein, ACellular Component: intracellular (GO:0005622), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
5 (443)4 (655)8 (596)IPR003892: Ubiquitin system component Cue
5 (444)5 (545)17 (290)IPR004182: GRAM
5 (445)20 (126) ()IPR004210: BESS motifMolecular Function: DNA binding (GO:0003677)
5 (446)7 (389)12 (400)IPR004299: Membrane bound O-acyl transferase, MBOAT
5 (447)5 (548)5 (885)IPR004364: tRNA synthetase, class II (D, K and N)Molecular Function: tRNA ligase activity (GO:0004812), Molecular Function: ATP binding (GO:0005524), Cellular Component: cytoplasm (GO:0005737), Biological Process: tRNA aminoacylation for protein translation (GO:0006418)
5 (448)4 (669)13 (379)IPR005112: dDENN
5 (449)4 (670)11 (432)IPR005113: uDENN
5 (450) ()1 (2384)IPR005119: LysR, substrate-binding
5 (451)10 (281) ()IPR005203: Hemocyanin, C-terminal
5 (452)8 (343) ()IPR005204: Hemocyanin, N-terminal
5 (453)2 (1181)5 (895)IPR005476: Transketolase, C-terminal
5 (454)3 (847)3 (1345)IPR005835: Nucleotidyl transferaseBiological Process: biosynthesis (GO:0009058), Molecular Function: nucleotidyltransferase activity (GO:0016779)
5 (455)6 (466)11 (433)IPR006011: Syntaxin, N-terminalCellular Component: membrane (GO:0016020)
5 (456)15 (193)31 (150)IPR006026: Peptidase, metallopeptidasesBiological Process: proteolysis and peptidolysis (GO:0006508), Molecular Function: metallopeptidase activity (GO:0008237)
5 (457)6 (469)4 (1104)IPR006139: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic regionBiological Process: L-serine biosynthesis (GO:0006564), Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
5 (458)6 (470)4 (1105)IPR006140: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-bindingBiological Process: L-serine biosynthesis (GO:0006564), Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
5 (459)5 (554)13 (381)IPR006153: Sodium/hydrogen exchangerBiological Process: regulation of pH (GO:0006885), Molecular Function: solute:hydrogen antiporter activity (GO:0015299), Cellular Component: integral to membrane (GO:0016021)
5 (460)5 (557)5 (912)IPR006571: TLDc
5 (461)13 (220)5 (917)IPR006589: Alpha amylase, catalytic subdomainMolecular Function: alpha-amylase activity (GO:0004556), Biological Process: carbohydrate metabolism (GO:0005975)
5 (462)7 (394)7 (682)IPR006596: Nucleotide binding protein, PINc
5 (463)5 (559)6 (780)IPR006630: RNA-binding protein Lupus La
5 (464)4 (691)10 (488)IPR006680: AmidohydrolaseMolecular Function: hydrolase activity (GO:0016787)
5 (465)5 (562)6 (786)IPR007109: Brix
5 (466)6 (474)5 (922)IPR007259: Spc97/Spc98Biological Process: microtubule cytoskeleton organization and biogenesis (GO:0000226), Cellular Component: spindle pole (GO:0000922), Cellular Component: microtubule organizing center (GO:0005815)
5 (467)15 (195)9 (546)IPR007484: Peptidase M28Biological Process: proteolysis and peptidolysis (GO:0006508), Molecular Function: peptidase activity (GO:0008233)
5 (468)6 (476)14 (359)IPR008211: Laminin, N-terminalCellular Component: extracellular matrix (sensu Metazoa) (GO:0005578)
5 (469)3 (902)10 (490)IPR008273: Cellular retinaldehyde-binding/triple function, N-terminal
5 (470)5 (569)1 (2770)IPR008774: A2 PhospholipaseMolecular Function: phospholipase A2 activity (GO:0004623), Molecular Function: calcium ion binding (GO:0005509), Cellular Component: extracellular region (GO:0005576), Biological Process: phospholipid metabolism (GO:0006644)
5 (471)2 (1331)9 (549)IPR009886: HCaRG
5 (472)6 (479)12 (403)IPR010625: CHCH
5 (473)10 (290)3 (1479)IPR011611: PfkB
5 (474)5 (575)4 (1164)IPR011706: Multicopper oxidase, type 2Molecular Function: copper ion binding (GO:0005507), Molecular Function: oxidoreductase activity (GO:0016491)
5 (475)4 (718) ()IPR011707: Multicopper oxidase, type 3Molecular Function: copper ion binding (GO:0005507), Molecular Function: oxidoreductase activity (GO:0016491)
5 (476)6 (482)6 (805)IPR011765: Peptidase M16, N-terminal
4 (477)2 (930)18 (260)IPR000001: Kringle
4 (478)5 (484)15 (304)IPR000038: Cell division/GTP binding proteinMolecular Function: GTP binding (GO:0005525), Biological Process: cell cycle (GO:0007049)
4 (479)4 (577)3 (1172)IPR000040: Acute myeloid leukemia 1 protein (AML 1)/RuntMolecular Function: DNA binding (GO:0003677), Molecular Function: ATP binding (GO:0005524), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
4 (480)6 (408)4 (974)IPR000120: AmidaseMolecular Function: amidase activity (GO:0004040)
4 (481)9 (291)20 (231)IPR000157: TIRMolecular Function: transmembrane receptor activity (GO:0004888), Cellular Component: membrane (GO:0016020)
4 (482)7 (353)6 (701)IPR000194: H+-transporting two-sector ATPase, alpha/beta subunit, central regionMolecular Function: ATP binding (GO:0005524), Biological Process: ATP synthesis coupled proton transport (GO:0015986), Cellular Component: proton-transporting two-sector ATPase complex (GO:0016469), Molecular Function: hydrogen-transporting ATP synthase activity, rotational mechanism (GO:0046933), Molecular Function: hydrogen-transporting ATPase activity, rotational mechanism (GO:0046961)
4 (483)5 (487)3 (1177)IPR000246: Peptidase T2, asparaginase 2Molecular Function: asparaginase activity (GO:0004067), Biological Process: glycoprotein catabolism (GO:0006516)
4 (484)4 (581)9 (499)IPR000261: EPS15 homology (EH)
4 (485)5 (488)11 (408)IPR000286: Histone deacetylase superfamily
4 (486)4 (582)3 (1182)IPR000323: Copper type II, ascorbate-dependent monooxygenaseMolecular Function: monooxygenase activity (GO:0004497), Molecular Function: copper ion binding (GO:0005507)
4 (487)5 (489)16 (294)IPR000327: POUMolecular Function: transcription factor activity (GO:0003700), Cellular Component: nucleus (GO:0005634), Biological Process: regulation of transcription, DNA-dependent (GO:0006355)
4 (488)3 (739)4 (978)IPR000352: Class I peptide chain release factorMolecular Function: translation release factor activity (GO:0003747), Biological Process: translational termination (GO:0006415)
4 (489)6 (412)6 (704)IPR000402: Na+/K+ ATPase, beta subunitMolecular Function: sodium:potassium-exchanging ATPase activity (GO:0005391), Biological Process: potassium ion transport (GO:0006813), Biological Process: sodium ion transport (GO:0006814), Cellular Component: membrane (GO:0016020)
4 (490)2 (947)5 (812)IPR000432: DNA mismatch repair protein MutS, C-terminalMolecular Function: damaged DNA binding (GO:0003684), Molecular Function: ATP binding (GO:0005524), Biological Process: mismatch repair (GO:0006298)
4 (491)1 (1423)22 (207)IPR000558: Histone H2BCellular Component: nucleosome (GO:0000786), Molecular Function: DNA binding (GO:0003677), Cellular Component: nucleus (GO:0005634), Biological Process: nucleosome assembly (GO:0006334), Biological Process: chromosome organization and biogenesis (sensu Eukaryota) (GO:0007001)
4 (492)4 (588)4 (981)IPR000583: Glutamine amidotransferase, class-IIBiological Process: metabolism (GO:0008152)
4 (493)4 (590)12 (386)IPR000648: Oxysterol-binding proteinBiological Process: steroid metabolism (GO:0008202)
4 (494)4 (591)4 (989)IPR000649: Initiation factor 2B relatedBiological Process: cellular biosynthesis (GO:0044249)
4 (495)7 (357)6 (709)IPR000793: H+-transporting two-sector ATPase, alpha/beta subunit, C-terminalBiological Process: ATP biosynthesis (GO:0006754), Biological Process: ATP synthesis coupled proton transport (GO:0015986), Cellular Component: proton-transporting two-sector ATPase complex (GO:0016469), Molecular Function: hydrogen-transporting ATP synthase activity, rotational mechanism (GO:0046933), Molecular Function: hydrogen-transporting ATPase activity, rotational mechanism (GO:0046961)
4 (496)5 (500)3 (1195)IPR000814: TATA-box bindingMolecular Function: DNA binding (GO:0003677), Molecular Function: RNA polymerase II transcription factor activity (GO:0003702), Cellular Component: nucleus (GO:0005634), Cellular Component: transcription factor TFIID complex (GO:0005669), Biological Process: regulation of transcription, DNA-dependent (GO:0006355), Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367)
4 (497)2 (969)1 (2077)IPR000897: GTP-binding signal recognition particle SRP54, G-domainMolecular Function: RNA binding (GO:0003723), Molecular Function: GTP binding (GO:0005525), Cellular Component: signal recognition particle (sensu Eukaryota) (GO:0005786), Biological Process: SRP-dependent cotranslational protein-membrane targeting (GO:0006614)
4 (498)2 (971)9 (508)IPR000906: ZU5
4 (499)5 (502)13 (365)IPR000949: ELM2
4 (500)7 (360) ()IPR000990: InnexinCellular Component: gap junction (GO:0005921)